Amphotericin B manufacturers and suppliers

Amphotericin B suppliers

Properties

Melting point:: >170°C

alpha: D24 +333° (acidic DMF); -33.6° (0.1N methanolic HCl)

Boiling point:: 804.34°C (rough estimate)

Density: 1.34

refractive index: 1.5280 (estimate)

storage temp.: 2-8°C

solubility: sterile water: 20 mg/mL as a stock solution. Stock solutions should be stored at −20°C. Stable at 37°C for 3 days.

form: powder

pka: pKa ～5.7(DMF/H2O) (Uncertain)

color: yellow

Water Solubility: <0.1 g/100 mL at 21 ºC

Sensitive: Moisture & Light Sensitive

Merck: 13,590

BRN: 78342

Stability:: Stable, but may be light sensitive. Incompatible with strong oxidizing agents.

InChIKey: APKFDSVGJQXUKY-INPOYWNPSA-N

Safety Information

Symbol(GHS): GHS08

Signal word: Danger

Hazard statements: H372

Precautionary statements: P260-P264-P270-P314-P501

Hazard Codes: C,Xi,Xn,T

Risk Statements: 36/37/38-22-40-23/24/25

Safety Statements: 26-36/37/39-45-36-60-37

RIDADR: UN 1759 8/PG 3

WGK Germany: 3

RTECS: BU2625000

F: 8-10-21

HazardClass: 6.1(b)

PackingGroup: III

HS Code: 29419090

Toxicity: LD50 in mice (mg/kg): 88 i.p., 4 i.v. (Keim)

Use

Amphotericin B (Funizone) is an antifungal macrolide antibiotic produced by Streptomyces nodosus that has been used as an alternative, albeit more toxic, drug to the antimonials. See also Amebiasis (Amebic Dysentery) . It acts as a leishmanicide against the visceral and mucocutaneous forms of the disease. To overcome its potentially severe nephrotoxicity, the drug must be administered over an extended period of time.

You can find Amphotericin B suppliers, manufacturers, and distributors from countries such as China, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.