Brefeldin A manufacturers and suppliers

Brefeldin A suppliers

Properties

Melting point:: 200-205 °C

Boiling point:: 492.7±45.0 °C(Predicted)

alpha: 93 º (C=2 IN MEOH)

Density: 1.108±0.06 g/cm3(Predicted)

vapor pressure: 0.56 hPa ( 20 °C)

Flash point:: 87 °C

storage temp.: Sealed in dry,Store in freezer, under -20°C

solubility: methanol: 10 mg/mL, clear, colorless to faintly yellow

pka: 12.92±0.60(Predicted)

form: Crystalline Powder

color: White to almost white

Water Solubility: Soluble in dimethylsulfoxide, dichloromethane and ethanol. Slightly soluble in water.

Merck: 13,1355

BRN: 25191

Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

InChIKey: QSECOIOBNZLGOD-OBCVZTHZSA-N

Safety Information

Symbol(GHS): GHS06

Signal word: Danger

Hazard statements: H301

Precautionary statements: P301+P310

Hazard Codes: Xn,T

Risk Statements: 22-25-36/37/38-20/21/22

Safety Statements: 24/25-45-36-26

RIDADR: UN 2811 6.1/PG 3

WGK Germany: 3

RTECS: GY8410000

Autoignition Temperature: 301 °C

HS Code: 29411090

Toxicity: LD50 i.p. in mice: >200 mg/kg (Haerri)

Use

Brefeldin A was isolated from Penicillium brefeldianum and recrystallised from aqueous MeOH/EtOAc or MeOH. Its solubility in H2O is 0.6mg/mL, 10mg/mL in MeOH and 24.9mg/mL in EtOH. The O-acetate recrystallises from Et2O/pentane and has m 130-131o, [] D +17o (c 0.95, MeOH). [Sigg Helv Chim Acta 47 1401 1964, UV and IR: H.rri et al. Helv Chim Acta 46 1235 1963, total synthesis: Kitahara et al. Tetrahedron 3021 1979, X-ray : Weber et al. Helv Chim Acta 54 2763 1971, Beilstein 18 III/IV 1220.]

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