Candesartan manufacturers and suppliers

Candesartan suppliers

Properties

Melting point:: 183-185°C

Boiling point:: 754.8±70.0 °C(Predicted)

Density: 1.41±0.1 g/cm3(Predicted)

RTECS: DD6671000

storage temp.: Inert atmosphere,Store in freezer, under -20°C

solubility: Soluble in DMSO (up to 40 mg/ml)

form: solid

pka: 2.06±0.10(Predicted)

color: White

Water Solubility: Soluble in ethyl acetate, methanol, water (<1 mg/ml at 25°C), DMSO (88 mg/ml at 25°C), and ethanol (1 mg/ml at 25°C).

Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302-H312-H315-H319-H332-H335

Precautionary statements: P261-P280-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes: Xn

Risk Statements: 20/21/22-36/37/38

Safety Statements: 26-36-60-36/37-9

HS Code: 29419000

Use

Candesartan, (+)-1-[[(cyclohexyloxy)carbonyl]-oxy]ethyl 2- ethoxy-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-benzimidazole-7-carboxylate(Atacand), like losartan, possesses the acidic tetrazole system,which most likely plays a role in binding to the angiotensin IIreceptor similarly to the acidic groups of angiotensin II. Also,the imidazole system has been replaced with a benzimidazolepossessing an ester at position. This ester must be hydrolyzedto the free acid. Fortunately, this conversion takesplace fairly easily because of the carbonate in the ester sidechain. This facilitates hydrolysis of the ester so much thatconversion to the free acid takes place during absorption fromthe gastrointestinal tract.

You can find Candesartan suppliers, manufacturers, and distributors from countries such as CHINA, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.