Capecitabine manufacturers and suppliers

Capecitabine suppliers

Properties

Melting point:: 110-121°C

Density: 1.49±0.1 g/cm3(Predicted)

Flash point:: 87℃

storage temp.: 2-8°C

solubility: H2O: soluble10mg/mL, clear (warmed)

pka: 5.41±0.40(Predicted)

form: powder

color: white to beige

Merck: 14,1754

InChIKey: GAGWJHPBXLXJQN-UORFTKCHSA-N

SMILES: C[C@H]1O[C@@H](N2C=C(F)C(NC(OCCCCC)=O)=NC2=O)[C@H](O)[C@@H]1O

Safety Information

Symbol(GHS): GHS08

Signal word: Danger

Hazard statements: H341-H350-H360FD

Precautionary statements: P201-P308+P313

Hazard Codes: T

Risk Statements: 45-60-61-68

Safety Statements: 53-22-36/37-45

WGK Germany: 3

RTECS: HA3852500

HS Code: 29349990

Use

Capecitabine is a new form of oral fluorinated pyrimidine drug. Capecitabine was developed by Roche Pharmaceuticals, and its commercial name is Xeloda. Capecitabine can change in vivo into 5- FU, an anti-metabolizim fluorine pyrimidine deoxynucleoside carbamate drug that targets cancer cells to inhibit cell division and disrupt RNA and protein synthesis. Its effects are significantly tied to the level of TP enzyme expression in neoplastic tissue and to DPD enzyme in vivo expression. It is suitable as further treatment for advanced primary or metastatic breast cancer patients who have not responded to paclitaxel or anthracycline antibiotics. As an anticancer drug, it is mostly used to treat advanced primary or metastatic breast cancer, as well as in treatment for non-small cell lung cancer, pancreatic cancer, bladder cancer, rectal cancer, colon cancer, gastric cancer, and other solid tumors. Many drugs such as taxanes (paclitaxel, docetaxel, mitomycin, cisplatin, etc.) can increase TP enzyme expression in neoplastic tissues and also have curative effects on gastric cancer. When used in combination with Capecitabine, these drugs can also improve Capecitabines anticancer abilities and produce synergistic effects.

You can find Capecitabine suppliers, manufacturers, and distributors from countries such as China, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.