Chloramphenicol palmitate manufacturers and suppliers

Chloramphenicol palmitate suppliers

Properties

Melting point:: 90 C

alpha: D26 +24.6° (c = 5 in ethanol)

Boiling point:: 691.6±55.0 °C(Predicted)

Density: 1.2354 (rough estimate)

refractive index: 1.7350 (estimate)

storage temp.: Store at RT.

solubility: DMSO (Slightly), Ethanol (Sparingly), Ethyl Acetate (Slightly)

pka: 10.69±0.46(Predicted)

color: White to Off-White

Water Solubility: 8.423ug/L(25 ºC)

λmax: 271nm(EtOH)(lit.)

Merck: 14,2077

BRN: 2826438

Stability:: Hygroscopic

Safety Information

Symbol(GHS): GHS08

Signal word: Warning

Hazard statements: H351

Precautionary statements: P280

Hazard Codes: Xn

Risk Statements: 40-36/37/38-20/21/22

Safety Statements: 36/37-36-26

WGK Germany: 3

RTECS: RT4735000

HS Code: 29414000

Use

Chloramphenicol palmitate is prepared by acylation of chloramphenicol with palmitic acid. Although chloramphenicol palmitate is a more hydrophobic drug which should enhance bioavailability, the primary advantage of the ester is to mask the taste of chloramphenicol in oral formulations. Chloramphenicol palmitate is significantly less active than chloramphenicol but acts as a prodrug, being readily hydrolysed by acid and esterase in the gut to release chloramphenicol.

You can find Chloramphenicol palmitate suppliers, manufacturers, and distributors from countries such as India, China and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.