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Cholesterol

CAS:
57-88-5
MF:
C27H46O
MW:
386.65

Properties

Melting point:
148-150 °C
alpha 
-36 º (c=2, dioxane)
Boiling point:
360 °C
Density 
1.06
refractive index 
1.5250 (estimate)
Flash point:
250 °C
storage temp. 
2-8°C
solubility 
H2O: 0.002 mg/mL
pka
15.03±0.70(Predicted)
form 
powder
color 
white
Specific Gravity
1.067
Water Solubility 
negligible
Merck 
14,2201
BRN 
1915888
InChIKey
HVYWMOMLDIMFJA-DPAQBDIFSA-N

Safety Information

Symbol(GHS) 

GHS06,GHS08
Signal word 
Danger
Hazard statements 
H302-H315-H319-H331-H336-H351-H361d-H372
Precautionary statements 
P201-P261-P304+P340+P312-P305+P351+P338-P308+P313-P403+P233
Hazard Codes 
Xn,Xi
Risk Statements 
10-48/20/22-40-38-22-36/37/38-67-36/38-20-63
Safety Statements 
24/25-22-36/37-36-26
RIDADR 
UN 1170 3/PG 3
WGK Germany 
1
RTECS 
FZ8400000
TSCA 
Yes
HS Code 
2906 13 10
HazardClass 
IRRITANT

Use

Cholesterol is a kind of derivatives of cyclopentane multiple hydrogen phenanthrenes and is an important component of various parts of membrane phase structure and myelin cells of human being. For the normal person with weight of 70 kg, the body contains about 140 grams of cholesterol. Since the early 18th century, people had already discovered cholesterol from gallstones. At 1816, Chemist Marshall named this kind of lipid-property substance as cholesterol. Cholesterol is widely found and distributed in animal bodies, and is especially most abundant in the brain and nerve tissue. It also has high content in the kidney, spleen, skin, liver and bile. The solubility of cholesterol is similar to that of the fat which is insoluble in water, but easily soluble in ether, chloroform and some other solvents. Cholesterol is closely related to the body tissues, bile acids and hormones. It is an indispensable substance of animal tissue cells, which is not only involved in the formation of cell membranes, but also as the precursor for the synthesis of bile acids, steroid hormones and vitamin D3. There are two sources of cholesterol with exogenous sources of cholesterol coming from dietary and endogenous sources coming from the body's own endogenous synthesis. The increased exogenous cholesterol can cause feedback inhibition of endogenous cholesterol synthesis. Fat in your diet can boost the cholesterol absorption. Cholesterol can be metabolized into bile acids or steroids. The absorption of cholesterol also depends on the cholesterol intake with high intake causing reduction of the percentage of absorption. The absorption percentage of cholesterol in people at high levels of intake is less than 10% with the rest part excreted through the feces. Dietary cholesterol is absorbed in the form of chylomicrons into the bloodstream. Because cholesterol can’t be dissolved in water and transported in the form of binding with lipoproteins in the blood. The main physiological function of cholesterol participating in forming cell membranes, myelin, brain, and can be further converted to bile acids and steroid hormones. There are two major lipoproteins which are involved in cholesterol transport: the low density lipoprotein (LDL) and high density lipoprotein (HDL). The former can transport cholesterol from the liver to the cells of whole body tissues, while the later one transports cholesterol from tissue cells back into the liver. The cholesterol level in the blood can reflect the overall metabolism condition of cholesterol. The total cholesterol content in the blood plasma of normal adult of empty stomach is about 2.83~5.17mmol/L. Abnormal cholesterol metabolism could easily lead to deposition of cholesterol in the blood vessel wall, forming atherosclerosis, causing coronary heart disease and stroke.

280 supplier list of "Cholesterol"

  • Product Name:Cholesterin
  • Products Intro:Purity: 0.99 | Package: 1g;25g;1kg;25kg;100kg | CustNote: Pharmaceutical grade
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  • Product Name:Cholesterol
  • Products Intro:Purity: 98%(Min,HPLC) | Package: 100g;1kg;5kg,10kg,25kg,50kg
  • Type of Enterprise: Trader
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  • Product Name:Cholesterol
  • Products Intro:Purity: 99% | Package: 100g,500g,1KG,10KG,100KG
  • Type of Enterprise: Reagent
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  • Main Products: Speciality Chemicals
  • Product Name:57-88-5
  • Products Intro:Purity: 0.99 | Package: 25KG,5KG;1KG;500G
  • Type of Enterprise: Trader
  • Country/Region: CHINA
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  • Product Name:Cholesterol
  • Products Intro:Purity: 90%+ | Package: 10mg, 25mg, 50mg, 100mg, Other scale please email Sales@pipitech.com | CustNote: Cholest-5-en-3β-ol
  • Type of Enterprise: Reagent
  • Country/Region: CHINA
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  • Product Name:Cholesterol
  • Products Intro:Purity: 99% | Package: 100g/ bag, 2 kg/ bag, 25kg/ carton or as required | CustNote: white crystalline solid
  • Type of Enterprise: Trader
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  • Product Name:Cholesterol
  • Products Intro:Purity: USP BP EP | Package: 1KG;5USD
  • Type of Enterprise: Reagent
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  • Product Name:Cholesterol
  • Products Intro:Purity: HPLC>=98% | Package: 200mg
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • TEL: 18017610038

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