Clindamycin palmitate hydrochloride manufacturers and suppliers

Clindamycin palmitate hydrochloride suppliers

Properties

Melting point:: 141-143°C

storage temp.: -20°C Freezer, Under Inert Atmosphere

solubility: DMSO (Slightly), Methanol (Slightly)

form: Solid

color: White to Off-White

InChIKey: GTNDZRUWKHDICY-ZLNNALEKSA-N

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H319

Precautionary statements: P264-P280-P305+P351+P338-P337+P313P

HS Code: 2941906000

Use

Clindamycin palmitate hydrochloride (Cleocin Pediatric) isthe hydrochloride salt of the palmitic acid ester ofcleomycin. The ester bond is to the 2-hydroxyl group of thelincosamine sugar. The ester serves as a tasteless prodrugform of the antibiotic, which hydrolyzes to clindamycin inthe plasma. The salt form confers water solubility to theester, which is available as granules for reconstitution intoan oral solution for pediatric use. Although absorption of thepalmitate is slower than that of the free base, there is littledifference in overall bioavailability of the two preparations.Reconstituted solutions of the palmitate hydrochloride arestable for 2 weeks at room temperature. Such solutionsshould not be refrigerated because thickening occurs thatmakes the preparation difficult to pour.

You can find Clindamycin palmitate hydrochloride suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.