Clotrimazole manufacturers and suppliers

Clotrimazole suppliers

Properties

Melting point:: 147-149°C

Boiling point:: 501.14°C (rough estimate)

Density: 1.1095 (rough estimate)

refractive index: 1.5940 (estimate)

storage temp.: 2-8°C

solubility: Soluble in chloroform, DMSO, DMF and alcohols

pka: pKa 4.7(EtOH 50%aq ) (Uncertain)

color: White to Almost white

Water Solubility: <10mg/L(25 ºC)

λmax: 556nm(Phosphate buffer sol.)(lit.)

Merck: 14,2417

InChI: InChI=1S/C22H17ClN2/c23-21-14-8-7-13-20(21)22(25-16-15-24-17-25,18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-17H

InChIKey: VNFPBHJOKIVQEB-UHFFFAOYSA-N

SMILES: C1N(C(C2=CC=CC=C2Cl)(C2=CC=CC=C2)C2=CC=CC=C2)C=CN=1

Safety Information

Symbol(GHS): GHS07,GHS09

Signal word: Warning

Hazard statements: H302-H315-H319-H410

Precautionary statements: P264-P270-P273-P301+P312-P302+P352-P305+P351+P338

Hazard Codes: Xn

Risk Statements: 22-36/38

Safety Statements: 26-36

WGK Germany: 3

RTECS: NI4377000

HS Code: 29332900

Toxicity: LD50 in male mice, rats (mg/kg): 923, 708 orally (Tettenborn)

Use

Clotrimazole formally also is an imidazole derivative because of the presence of an imidazole ring in its structure. It is believed that, like miconazole, econazole, and other “pure” representatives of the imidazole class, it also inhibits the biosynthesis of ergosterin in the cytoplasmatic membrane of fungi. In terms of pharmacological action, clotrimazole is very similar to miconazole. It has a broad spectrum of antifungal activity. It is effective with respect to dermatophytes, and it also has an antimicrobial effect against streptococci and staphylococci. It is also effective with respect to trichomonases. It is very widely used, both externally and vaginally for treating superficial infections.

You can find Clotrimazole suppliers, manufacturers, and distributors from countries such as CHINA, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.