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ChemicalBook >> CAS DataBase List >>Docetaxel

Docetaxel suppliers

Docetaxel

CAS:
114977-28-5
MF:
C43H53NO14
MW:
807.88

Properties

Melting point:
186-192 °C (dec.)
alpha 
-36 º (c=0.74,EtOH)
Boiling point:
900.5±65.0 °C(Predicted)
Density 
1.38
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
Practically insoluble in water, freely soluble in anhydrous ethanol, soluble in methylene chloride.
pka
11.20±0.46(Predicted)
color 
White
Water Solubility 
Soluble in dimethyl sulfoxide and ethanol. Insoluble in water.
Merck 
14,3397
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
InChIKey
BEDLLNJKXXVTSX-LWWLJZAUSA-N
LogP
2.456 (est)

Safety Information

Symbol(GHS) 
GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word 
Danger
Hazard statements 
H315-H319-H341-H360D-H362-H372
Precautionary statements 
P202-P260-P263-P302+P352-P305+P351+P338-P308+P313
Hazard Codes 
Xi
Risk Statements 
36/37/38-61
Safety Statements 
26-36/37-53-45
RIDADR 
1544
WGK Germany 
3
RTECS 
DA4172750
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29322090
Toxicity
LD50 intravenous in dog: 2500ug/kg

Use

Docetaxel, a semi-synthetic product from the taxoid family, was launched in 1995 first in South Africa and subsequently in several other markets for the treatment of ovarian, breast and non-small cell lung cancers. Like the naturally occurring antitumor agent paclitaxel, the first marketed taxoid, docetaxel promotes both the rate and extent of tubulin assembly into stable microtubules and inhibits their depolymerization. It acts as a mitotic spindle poison and induces a mitotic block in proliferating cells. This mechanism of action for taxoids is unique from other classes of anticancer agents. Docetaxel was reported to be twice as potent as paclitaxel in several in vitro protocols and also exhibit higher cytotoxicity. Clinical trials are on going for docetaxel for other types of tumors including pancreatic, gastric, head and neck cancers and soft tissue sarcomas.

597 supplier list of "Docetaxel"

  • Product Name:Docetaxel
  • Products Intro:Purity: 99% | Package: 100G; 1KG; 5KG; 25KG | CustNote: Pharmaceutical grade
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Shilajit,herb extract,Creatine Monohydrate,Curcumin,Nicotinamide
  • Product Name:Docetaxel anhydrous
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: (7a,17b)-7-(9-Bromononyl)-estra-1,3,5(10)-triene-3,17-diol 17-acetate,4,4,5,5,5-Pentafluoro-1-pentanol,L-proline,Sodium,4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoate,Cefprozil
  • Product Name:Docetaxel
  • Products Intro:Purity: 0.99 | Package: 5KG;1KG
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: cas 1451-83-8,cas 5449-12-7,cas 79099-07-3,Trenbolone Acetate,RAD-140

$0.00-0.00 / 1kg

  • Product Name:Docetaxel
  • Products Intro:Purity: 99.9% | Package: 1kg;|25kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: 2-Chloromalonaldehyde,(R)-5,7-difluorochroman-4-ol,Cyclobutanecarboxylic acid,(Bromomethyl)cyclobutane,5-Amino-4-imidazolecarboxamide

$0.00/ 25kg

  • Product Name:Docetaxel
  • Products Intro:Purity: 99%|Package: 25kg;0.00;USD
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: Plant extract,probiotics,API,cosmetics raw materials,food additives
  • Product Name:Docetaxel
  • Products Intro:Purity: 98%(Min,HPLC) | Package: 100g;1kg;5kg,10kg,25kg,50kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: 1159983-30-8,89466-59-1,149739-51-5,104901-79-3,10541-83-0
  • Product Name:Docetaxel
  • Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:Docetaxel
  • Products Intro:Purity: As coa | Package: As request | CustNote: 114977-28-5
  • Company Type: Trader
  • Country/Region: CHINA
  • Product Name:Docetaxel
  • Products Intro:Purity: 0.99 | Package: 5MG;10MG;50MG;100MG,1G,5G
  • Company Type: Reagent
  • Country/Region: CHINA

$1.00/ 1KG

  • Product Name:Docetaxel
  • Products Intro:Purity: 98% | Package: 1KG;1USD
  • Company Type: Reagent
  • Country/Region: CHINA
  • Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
You can find Docetaxel suppliers, manufacturers, and distributors from countries such as CHINA, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

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