Entacapone suppliers
Entacapone
- CAS:
- 130929-57-6
- MF:
- C14H15N3O5
- MW:
- 305.29
Suppliers by country/region
Company Type
Properties
- Melting point:
- 162-1630C
- Boiling point:
- 526.6±50.0 °C(Predicted)
- Density
- 1.392±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble20mg/mL, clear
- form
- powder
- pka
- pKa ~4.5(at 25℃)
- color
- white to light brown
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
- InChIKey
- JRURYQJSLYLRLN-BJMVGYQFSA-N
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319
- Precautionary statements
- P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
- WGK Germany
- 3
- HS Code
- 2926900005
Use
Entacapone was introduced in Finland, Germany and Sweden as an adjunctive treatment with L-dopa in Parkinson’s disease. Entacapone is the second drug in its class to reach the market; it can be obtained by basecatalyzed condensation of the corresponding benzaldehyde with a cyanoacetamide. Entacapone is a highly selective and orally-active catechol-0- methyltransferase (COMT) inhibitor ; by inhibiting metabolism of L-dopa when given as an adjuvant in patients with Parkinson’s disease, Entacapone markedly prolongs the effects of L-dopa and improves its bioavailability. Results from clinical studies showed that 200mglday Entacapone coadministered with L-dopa lowered the dose of the latter required to reduce fluctuations in motor performance.
380 supplier list of "Entacapone"
$40.00-40.00 / 1kg
- Product Name:Entacapone
- Products Intro:Purity: 0.99|Package: 1kg;40.00;USD|1kg;40.00;USD|1kg;40.00;USD
- Company Type: Manufacturer
- Country/Region: CHINA
- Main Products: lead acetate,Lead oxide,PMK ethyl glycidate,BMK Glycidic Acid,Diethyl(phenylacetyl)malonate
$2.00/ 1kg
- Product Name:Entacapone
- Products Intro:Purity: 99% | Package: 1kg;2USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
$100.00/ 25kg
- Product Name:Entacapone
- Products Intro:Purity: 99 | Package: 25kg;100USD
- Company Type: Service provider
- Country/Region: CHINA
- Main Products: carbomer,lead acetate,phenylacetamide,Xylazine,Xylazine hcl
-
10mg$53.0050mg$101.00100mg$150.00200mg$225.00
- Product Name:Entacapone
- Products Intro:Brand:TargetMol | Product Number:T2216 | Purity:100%|99.79%|98.88%
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits