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ChemicalBook >> CAS DataBase List >>Entacapone

Entacapone suppliers

Entacapone

CAS:
130929-57-6
MF:
C14H15N3O5
MW:
305.29

Properties

Melting point:
162-1630C
Boiling point:
526.6±50.0 °C(Predicted)
Density 
1.392±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: soluble20mg/mL, clear
form 
powder
pka
pKa ~4.5(at 25℃)
color 
white to light brown
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey
JRURYQJSLYLRLN-BJMVGYQFSA-N

Safety Information

Symbol(GHS) 
GHS hazard pictograms
GHS07
Signal word 
Warning
Hazard statements 
H315-H319
Precautionary statements 
P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
WGK Germany 
3
HS Code 
2926900005

Use

Entacapone was introduced in Finland, Germany and Sweden as an adjunctive treatment with L-dopa in Parkinson’s disease. Entacapone is the second drug in its class to reach the market; it can be obtained by basecatalyzed condensation of the corresponding benzaldehyde with a cyanoacetamide. Entacapone is a highly selective and orally-active catechol-0- methyltransferase (COMT) inhibitor ; by inhibiting metabolism of L-dopa when given as an adjuvant in patients with Parkinson’s disease, Entacapone markedly prolongs the effects of L-dopa and improves its bioavailability. Results from clinical studies showed that 200mglday Entacapone coadministered with L-dopa lowered the dose of the latter required to reduce fluctuations in motor performance.

380 supplier list of "Entacapone"

$40.00-40.00 / 1kg

  • Product Name:Entacapone
  • Products Intro:Purity: 0.99|Package: 1kg;40.00;USD|1kg;40.00;USD|1kg;40.00;USD
  • Company Type: Manufacturer
  • Country/Region: CHINA
  • Main Products: lead acetate,Lead oxide,PMK ethyl glycidate,BMK Glycidic Acid,Diethyl(phenylacetyl)malonate
  • Product Name:(E)-2-cyano-3-(5-(dihydroxyamino)-3,4-dioxocyclohexa-1,5-dienyl)-N,N-diethylacrylamide
  • Products Intro:Purity: 98%(Min.HPLC) | Package: 100g;1kg;5kg,10kg,25kg,50kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: 1159983-30-8,89466-59-1,149739-51-5,104901-79-3,10541-83-0
  • Product Name:(E)-2-cyano-3-(5-(dihydroxyamino)-3,4-dioxocyclohexa-1,5-dienyl)-N,N-diethylacrylamide
  • Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
  • Company Type: Trader
  • Country/Region: CHINA

$2.00/ 1kg

  • Product Name:Entacapone
  • Products Intro:Purity: 99% | Package: 1kg;2USD
  • Company Type: Reagent
  • Country/Region: CHINA
  • Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
  • Product Name:Entacapone
  • Products Intro:Purity: >98% | Package: 500mg | CustNote: BOC Sciences also provides custom synthesis services for Entacapone.
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Product Name:Entacapone
  • Products Intro:Purity: 0.98 | Package: 1kg,2kg,5kg,10kg,25kg
  • Company Type: Trader
  • Country/Region: CHINA
  • Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL
  • Product Name:entacapone
  • Products Intro:Purity: 0.99 | Package: 1kg
  • Company Type: Trader
  • Country/Region: CHINA

$100.00/ 25kg

  • Product Name:Entacapone
  • Products Intro:Purity: 99 | Package: 25kg;100USD
  • Company Type: Service provider
  • Country/Region: CHINA
  • Main Products: carbomer,lead acetate,phenylacetamide,Xylazine,Xylazine hcl
  • 10mg$53.00
    50mg$101.00
    100mg$150.00
    200mg$225.00
  • Product Name:Entacapone
  • Products Intro:Brand:TargetMol | Product Number:T2216 | Purity:100%|99.79%|98.88%
  • Company Type: Trader
  • Country/Region: UNITED STATES
  • Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
  • Product Name:Entacapone
  • Products Intro:Purity: 0.99 | Package: 5KG;1KG
  • Company Type: Trader
  • Country/Region: CHINA
You can find Entacapone suppliers, manufacturers, and distributors from countries such as China, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.

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