Fisetin manufacturers and suppliers

Fisetin suppliers

Properties

Melting point:: >330 °C(lit.)

Boiling point:: 348.61°C (rough estimate)

Density: 1.2981 (rough estimate)

refractive index: 1.4413 (estimate)

storage temp.: Sealed in dry,Store in freezer, under -20°C

solubility: DMSO (Slightly), Methanol (Slightly)

form: Solid

Colour Index: 75620

pka: 6.83±0.40(Predicted)

color: Pale Yellow to Very Dark Yellow

Merck: 14,4088

BRN: 292829

Stability:: Hygroscopic

InChI: InChI=1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H

InChIKey: XHEFDIBZLJXQHF-UHFFFAOYSA-N

SMILES: C1(C2=CC=C(O)C(O)=C2)OC2=CC(O)=CC=C2C(=O)C=1O

LogP: 1.970 (est)

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H315-H319-H335

Precautionary statements: P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Risk Statements: 36/37/38

Safety Statements: 22-24/25

WGK Germany: 3

RTECS: LK9250000

F: 10

TSCA: Yes

HS Code: 29329990

Use

Fisetin is a plant polyphenol from the flavonoid group. It occurs in fruits and vegetablesincluding persimmons, strawberries, onions, cucumbers, and apples. It is anantioxidant, exerts anticarcinogenic effects in HCT-116 (human colon carcinoma)cells, and modulates protein kinase and lipid kinase pathways (Wang et al. 2012).Fisetin alter signaling pathway like MAPK, NF-κB, activators of transcription(JAK/STAT), Janus kinase/signal transducers, phosphoinositide-3-kinase-proteinkinase (PI3K/Akt), Wnt, and mammalian target of rapamycin (mTOR), therebyleading to cell cycle arrest in HL-60 cells (human acute promyelocytic leukemiacells) (Singh et al. 2016b). Thus, it exhibits inhibitory effects on adhesion, migration,invasion, and multidrug resistance (Suh et al. 2009).

You can find Fisetin suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.