Homoharringtonine suppliers
Homoharringtonine
- CAS:
- 26833-87-4
- MF:
- C29H39NO9
- MW:
- 545.63
Suppliers by country/region
Company Type
Properties
- Melting point:
- 144-146 C
- Boiling point:
- 619.03°C (rough estimate)
- Density
- 1.2395 (rough estimate)
- refractive index
- 1.6290 (estimate)
- storage temp.
- 2-8°C
- solubility
- DMSO: soluble20mg/mL, clear
- pka
- 11.60±0.29(Predicted)
- form
- powder
- color
- white to beige
- optical activity
- [α]/D -120 to -140°, c = 1 in chloroform-d
- InChIKey
- DJIVDDPFKDEQIR-XSEHADPMSA-N
Safety Information
- Symbol(GHS)
GHS06
- Signal word
- Danger
- Hazard statements
- H300+H310+H330
- Precautionary statements
- P262-P280-P301+P310+P330-P302+P352+P310-P304+P340+P310
- Hazard Codes
- T+,Xi
- Risk Statements
- 26/27/28-36/37/38-28
- Safety Statements
- 36/37/39-45-27-26-36/37-28
- RIDADR
- UN 1544 6.1/PG 2
- WGK Germany
- 3
- RTECS
- FK0260000
- HazardClass
- 6.1(a)
- PackingGroup
- II
Use
The homoharringtonine is synthesized using -methyl--caprolactone (1) and ethanol as starting materials via ring opening and elimination of ethyl 5-methyl-4-hexenoate (2), 2 has condensation reaction with diethyl oxalate to give diethyl 2-(3-methyl-2-butenyl) malonate (3), 3 has -decarboxylation reaction with aqueous dimethylsulfoxide in the presence of sodium chloride to generate 6-methyl-2-oxo-5-heptenoic acid ethyl ester (4); 4 is subject to alkaline hydrolysis, oxalylation and further acylation of cephalotaxine to obtain 6-methyl-2-Oxo-5-heptenoic acid cephalomannine ester (6) and then subjected to a Rafalmacky reaction to give methyl 2-hydroxy-2-(4-methyl-3-pentenyl) succinate Cephalotaxine ester (7), 7 is subject to mercury hydroxylation and mercury removal reaction to obtain the end product, homoharringtonine. The reaction scheme is as follows: Figure 2 is a chemical reaction route map for the laboratory synthesis of homoharringtonine.
235 supplier list of "Homoharringtonine"
$0.00-0.00 / 1kg
- Product Name:Homoharringtonine
- Products Intro:Purity: >=98% | Package: 1kg;|5kg;|25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Ceramides,Phytosphingosine,Ectoine,Complex ceramide emulsion,Water soluble ceramides
- Product Name:Homoharringtonine
- Products Intro:Purity: 99% | Package: 100g ;1KG ;5KG 25KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: OLED/LCD chemicals,Reactive Mesogens,Silane,Silicon
- Product Name:TIANFU-CHEM Homoharringtonine
- Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
$1.00/ 1kg
- Product Name:Homoharringtonine
- Products Intro:Purity: 95%-99% | Package: 1kg;1USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
- Product Name:Homoharringtonine
- Products Intro:Purity: 0.98 | Package: 10mg;20mg;50mg;100mg;500mg | CustNote: Can Be Customized in Bulk
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Mogroside V,Methysticin,Sarsasapogenin,20(R)-Ginsenoside Rg3,Ginsenoside CK
- Product Name:Homoharringtonine
- Products Intro:Purity: 0.99 | Package: 1g;25g;1kg;25kg;100kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Homoharringtonine
- Products Intro:Purity: 0.98 | Package: 1kg，2kg，5kg，10kg，25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL
- Product Name:Homoharringtonine
- Products Intro:Purity: 99% | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Homoharringtonine
- Products Intro:Purity: 99.0% | Package: 100g;1kg;5kg;25kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Homoharringtonine
- Products Intro:Package: 1KG;5KG;100KG;1000KG
- Company Type: Trader
- Country/Region: CHINA