Ibudilast suppliers
Ibudilast
- CAS:
- 50847-11-5
- MF:
- C14H18N2O
- MW:
- 230.31
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Properties
- Melting point:
- 53-54°C
- Boiling point:
- 175°C/7.5mmHg(lit.)
- Density
- 1.09
- refractive index
- 1.5500 (estimate)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO: 28 mg/mL, soluble
- form
- solid
- pka
- 1.22±0.30(Predicted)
- color
- white
- Merck
- 14,4879
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
- InChI
- InChI=1S/C14H18N2O/c1-9(2)13-12(14(17)10(3)4)11-7-5-6-8-16(11)15-13/h5-10H,1-4H3
- InChIKey
- ZJVFLBOZORBYFE-UHFFFAOYSA-N
- SMILES
- C(C1=C2N(N=C1C(C)C)C=CC=C2)(=O)C(C)C
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H302-H315-H319-H335
- Precautionary statements
- P261-P264-P270-P301+P312-P302+P352-P305+P351+P338
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 3
- RTECS
- UR0711200
- HS Code
- 2933.99.8290
- Toxicity
- LD50 i.v. in mice: 260 mg/kg (Irikura, 1973)
Use
Ibudilast is a leukomene antagonist and phosphodiesterase inhibitor useful in the treatment of bronchial asthma. It antagonizes leukotriene D4-induced contractions of guinea pig ileum and tracheal muscles in virro, and inhibits eosinophil accumulation in vivo.
254 supplier list of "Ibudilast"
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