Imperatorin manufacturers and suppliers

Imperatorin suppliers

Properties

Melting point:: 98-100°C

Boiling point:: 333.4°C (rough estimate)

Density: 1.1311 (rough estimate)

refractive index: 1.4350 (estimate)

storage temp.: -20°C

solubility: DMSO: ≥5mg/mL

form: powder

color: off-white to light brown

λmax: 301nm(MeOH)(lit.)

Merck: 14,4925

InChIKey: OLOOJGVNMBJLLR-UHFFFAOYSA-N

LogP: 2.983 (est)

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P264-P270-P301+P312+P330-P501

Safety Statements: 24/25

WGK Germany: 3

RTECS: LV1575000

HS Code: 29419090

Use

Imperatorin is a kind of furocoumarin and phytochemical that present in citrus fruits. It could be isolated from Urena lobata L. (Malvaceae). It is biosynthesized from Umbelliferae in vivo. It has been found that it has anti-hypertrophic and anti-convulsant effects, and is useful in the HIV-1 research. Previous studies have shown that Imperatorin requires the transcription factor Sp1 to exert its inhibitory effect on the HIV-1. It can further inhibit the expression of cyclin D1 to cause cell cycle arrest at G1 stage. Moreover, it can suppress the HIV-1 replication inside the primary T lymphocytes and transformed cell lines. This inhibitory effect on HIV-1 can also be effectively observed in the HeLa cells. In addition, it has also been shown that it can cause apoptosis of human promyelocytic leukaemia via the cytochrome c/caspase-9 pathway.

You can find Imperatorin suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.