Indacaterol suppliers
Indacaterol
- CAS:
- 312753-06-3
- MF:
- C24H28N2O3
- MW:
- 392.49
Suppliers by country/region
Company Type
Properties
- Melting point:
- >165°C (dec.)
- Boiling point:
- 660.3±55.0 °C(Predicted)
- Density
- 1.27
- storage temp.
- -20°C Freezer, Under inert atmosphere
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 8.68±0.20(Predicted)
- form
- Solid
- color
- Off-White to Light Yellow
- InChIKey
- QZZUEBNBZAPZLX-QFIPXVFZSA-N
- SMILES
- N1C2=C(C([C@@H](O)CNC3CC4=C(C3)C=C(CC)C(CC)=C4)=CC=C2O)C=CC1=O
Safety Information
Use
Inhaled β2 adrenoceptor agonists are effective in the management of asthma and COPD, primarily through their bronchodilating properties. These drugs induce bronchodilation by causing direct relaxation of airway smooth muscle through activation of adenylate cyclase, which in turn increases intracellular cAMP levels. Indacaterol is the newest β2 agonist to reach the market. It is an ultra-long-acting agent with a duration of action suitable for once-a-day dosing. Indacaterol is supplied as an aerosol formulation of its maleate salt and is administered via a dry powder inhaler device. It is specifically approved for once-daily maintenance treatment of airflow obstruction in adult patients with COPD. In preclinical models, indacaterol is close to a full agonist at the human b2 adrenoceptor (Emax = 73 ± 1% of isoprenaline′s maximal effect, pEC50 = 8.06 ±0.02) while salmeterol displays only partial efficacy (38 ±1%). The functional selectivity profile of indacaterol over β1 human adrenoceptors is similar to that of formoterol, whereas its β3 adrenoceptor selectivity profile is similar to that of formoterol and salbutamol.
127 supplier list of "Indacaterol"
![5-[(1R)-2-[(5,6-DIETHYL-2,3-DIHYDRO-1H-INDEN-2-YL)AMINO]-1-HYDROXYETHYL]-8-HYDROXYQUINOLIN-2(1H)-ONE](https://img.chemicalbook.com/CompanyLogo/d89d97b5-e2b6-4934-ad8d-97ce609c517020210521134328.png)
- Product Name:5-[(1R)-2-[(5,6-DIETHYL-2,3-DIHYDRO-1H-INDEN-2-YL)AMINO]-1-HYDROXYETHYL]-8-HYDROXYQUINOLIN-2(1H)-ONE
- Products Intro:Purity: 99% | Package: USP EP CP
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmceutical,Optical Brightening,dyes
$2.00/ 1kg
- Product Name:Indacaterol
- Products Intro:Purity: 99%|Package: 1kg;2.00;USD
- Company Type: Manufacturer
- Country/Region: CHINA
- Main Products: Apixaban intermediates,Selpercatinib(LOXO-292),Ritlecitinib,Elacestrant,Lurasidone intermediates
$70.00-700.00 / 1kg
- Product Name:Indacaterol
- Products Intro:Purity: 0.99|Package: 1kg;70.00;USD|10kg;700.00;USD
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Fine Chemical,API,Raw Material,Pharmaceutical Compounds,Others
![2(1H)-Quinolinone,5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-](https://img.chemicalbook.com/CompanyLogo/info@tianfuchem.com2017111516254012159.jpg)
- Product Name:2(1H)-Quinolinone,5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-
- Products Intro:Purity: 99% | Package: 25KG;5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Indacaterol
- Products Intro:Purity: 98% | Package: 10MG;50MG;100MG,1G,5G,10G.100G
- Company Type: Reagent
- Country/Region: CHINA
$2.00/ 1kg
- Product Name:Indacaterol
- Products Intro:Purity: 99% | Package: 1kg;2USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
- Product Name:Indacaterol
- Products Intro:Purity: 0.98 | Package: 1kg，2kg，5kg，10kg，25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL
- Product Name:indacaterol
- Products Intro:Purity: 99% | Package: 1mt
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Indacaterol
- Products Intro:Purity: 99.49% | Package: 10 mg；100 mg；200 mg；25 mg | CustNote: REAGENT;FOR LABORATORY USE ONLY
- Company Type: Trader
- Country/Region: UNITED STATES
- Main Products: Compound Libraries,Noval Small Molecucles,Nature Compounds,Inhibitory Antibodies,Life science Kits
- Product Name:Indacaterol
- Products Intro:Purity: 0.99 | Package: 5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: API(Active Pharmaceutical Ingredient),Lab Fine Chemical,Phytochemistry,Cosmetic Raw Materials