Metformin manufacturers and suppliers

Metformin suppliers

Properties

Melting point:: 199-200 °C

Boiling point:: 229.23°C (rough estimate)

Density: 1.0743 (rough estimate)

refractive index: 1.5760 (estimate)

storage temp.: Keep in dark place,Inert atmosphere,Room temperature

solubility: Acetonitrile (Slightly), Aqueous Acid (Slightly), Dichloromethane (Slightly)

form: Solid

pka: pKa 2.8(H2O,t =32) (Uncertain)

color: White to Light Brown

Water Solubility: Water: 50 mg/mL (387.12 mM)

BCS Class: 3

InChI: InChI=1S/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8)

InChIKey: XZWYZXLIPXDOLR-UHFFFAOYSA-N

SMILES: C(=N)(N(C)C)NC(=N)N

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P264-P270-P301+P312-P330-P501

Toxicity: LD50 oral in mouse: 1450mg/kg

Use

Metformin, N,N-dimethylimidodicarbonimidicdiamide hydrochloride (Glucophage), is a bisguanidine.This class of agents is capable of reducing sugar absorptionfrom the gastrointestinal tract. Also, they can decrease gluconeogenesiswhile increasing glucose uptake by muscles andfat cells. These effects, in turn, lead to lower blood glucoselevels. Unlike the sulfonylureas, these are not hypoglycemicagents but rather can act as antihyperglycemics. This differencein nomenclature is caused by the inability of these agentsto stimulate the release of insulin from the pancreas. Often,metformin is coadministered with the nonsulfonylureas to improvethe efficacy of those agents.

You can find Metformin suppliers, manufacturers, and distributors from countries such as China, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.