Mosapride manufacturers and suppliers

Mosapride suppliers

Properties

Melting point:: 151-153°C

Boiling point:: 549.2±50.0 °C(Predicted)

Density: 1.272±0.06 g/cm3(Predicted)

storage temp.: Keep in dark place,Sealed in dry,Room Temperature

solubility: DMSO (Slightly), Methanol (Slightly)

form: Solid

pka: 13.52±0.46(Predicted)

color: White to Off-White

Safety Information

Use

Mosapride citrate, a new gastroprokinetic benzamide was introduced in Japan as Gasmotin for the relief of gastrointestinal symptoms in patients with chronic gastritis, gastro-oesophageal reflux, dyspepsia and post-surgery use. Mosapride is synthesized by final amidation between the corresponding benzoic acid, itself obtained in 3 steps from methyl 4-acetamido salicylate, and the appropriate 2-aminomethyl-morpholine. Mosapride is a 5-HT4 partial agonist without notable activity for D2, 5-HT1 , 5-HT2, alpha-1 and alpha-2 receptors. In dogs, mosapride was as potent as cisapride to stimulate antral and duodenal motility. In most of species including man, mosapride undergoes extensive cleavage to a N-debenzylated metabolite which retains partial 5-HT4 activity but has potent 5-HT3 antagonist activity.

You can find Mosapride suppliers, manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.