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N,N-Dimethylformamide

CAS:
68-12-2
MF:
C3H7NO
MW:
73.09

Properties

Melting point:
-61 °C (lit.)
Boiling point:
153 °C (lit.)
alpha 
0.94 º
Density 
0.944 g/mL (lit.)
vapor density 
2.5 (vs air)
vapor pressure 
2.7 mm Hg ( 20 °C)
refractive index 
n20/D 1.430(lit.)
Flash point:
136 °F
storage temp. 
Store at +5°C to +30°C.
solubility 
water: miscible
form 
Powder
pka
-0.44±0.70(Predicted)
color 
APHA: ≤15
Odor
Faint, ammonia-like odor detectable at 100 ppm
Relative polarity
0.386
PH
7 (200g/l, H2O, 20℃)
explosive limit
2.2-16%(V)
Odor Threshold
1.8ppm
Water Solubility 
soluble
Sensitive 
Hygroscopic
λmax
λ: 270 nm Amax: 1.00
λ: 275 nm Amax: 0.30
λ: 295 nm Amax: 0.10
λ: 310 nm Amax: 0.05
λ: 340-400 nm Amax: 0.01
Merck 
14,3243
BRN 
605365
Exposure limits
NIOSH REL: TWA 10 ppm (30 mg/m3), IDLH 500 ppm; OSHA PEL: TWA 10 ppm; ACGIH TLV: TWA 10 ppm (adopted).
InChIKey
ZMXDDKWLCZADIW-UHFFFAOYSA-N

Safety Information

Symbol(GHS) 

GHS08,GHS02,GHS07,GHS05,GHS06
Signal word 
Danger
Hazard statements 
H312-H332-H302-H318-H331-H341-H370-H372-H360-H226-H312+H332-H319-H360D
Precautionary statements 
P202-P233-P240-P241+P242+P243-P260-P264-P270-P271-P301+P312+P330-P303+P361+P353-P304+P340+P311-P305+P351+P338+P310-P307+P311-P403+P233-P405-P501-P201-P280-P308+P313-P305+P351+P338-P210-P261-P370+P378-P501a
Hazard Codes 
T
Risk Statements 
61-20/21-36
Safety Statements 
53-45
RIDADR 
UN 2265 3/PG 3
WGK Germany 
1
RTECS 
LQ2100000
3-10
Autoignition Temperature
445 °C
Hazard Note 
Toxic
TSCA 
Yes
HazardClass 
3
PackingGroup 
III
HS Code 
29241990
Toxicity
LD50 in mice, rats (ml/kg): 6.8, 7.6 orally; 6.2, 4.7 i.p. (Bartsch)

Use

N,N-Dimethylformamide (DMF) is a clear liquid that has been widely used in industries as a solvent, an additive, or an intermediate because of its extensive miscibility with water and most common organic solvents. Dimethylformamide is primarily used as an industrial solvent. Dimethylformamide solutions are used toprocess polymer fibers, films, and surface coatings; to permit easy spinning of acrylic fibers; to produce wire enamels, and as a crystallization medium in the pharmaceutical industry. DMF can also be used for formylation with alkyllithium or Grignard reagents. It is used as a reagent in Bouveault aldehyde synthesis and also in Vilsmeier-Haack reaction. It acts as a catalyst in the synthesis of acyl chlorides. It is used for separating and refining crude from olefin gas. DMF along with methylene chloride acts as a remover of varnish or lacquers. It is also used in the manufacture of adhesives, fibers and films. N,N-Dimethylformamide (DMF) is a solvent with a low evaporation rate, useful for preparing solutions with a variety of hydrophobic organic compounds used in molecular biology applications. N,N-Dimethylformamide was used to solubilize MTT crystals in cell viability assays.It was also used in feruloyl esterase activity assay in molds exhibiting high activity of the enzyme. The world-wide consumption of DMF in 2001 was approximately 285, 000 metric tonnes and most of that was used as an industrial solvent.

521 supplier list of "N,N-Dimethylformamide"

    US $2.00/ 20L

  • Product Name:N,N-Dimethylformamide
  • Products Intro:Purity: 99%|Package: 20L;2USD
  • Type of Enterprise: Trader
  • Country/Region: CHINA
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  • Product Name:N,N-Dimethylformamide
  • Products Intro:Purity: 99.9% | Package: 1KG;5USD
  • Type of Enterprise: Reagent
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  • TEL: 86-0551-65418684 18949823763
  • Product Name:dimethylformamide
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  • Main Products: Octane booster,lubricant additve,specialty chemicals,ingredients

    US $10.00/ 1KG

  • Product Name:N,N-Dimethylformamide
  • Products Intro:Purity: 99%|Package: 1KG;10USD
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • Main Products: phenactin,4-Methylpropiophenone 5337-93-9,288573-56-8,443998-65-0

    US $20.00/ 1g

  • Product Name:DMF
  • Products Intro:Purity: 99.9%|Package: 1g;20USD
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • TEL: 13373514458

    US $48.00-40.00 / 1公斤

  • Product Name:N,N-Dimethylformamid
  • Products Intro:Purity: 99%|Package: 1公斤;48USD|10公斤;45USD|100公斤;40USD
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • TEL: 18575736215
  • Main Products: Chemical raw materials,Medical apparatus and instruments

    US $485.00/ 190Kg/Drum

  • Product Name:N,N-Dimethylformamide
  • Products Intro:Purity: 99.9%|Package: 190Kg/Drum;485USD
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • Main Products: Tetrahydrofuran,Acetonitrile,Aniline,Phenol,N,N-Dimethylacetamide
  • Product Name:N,N-Dimethylformamide
  • Products Intro:Purity: 99%min|Package: 25Kg/Drum;100USD
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • Product Name:DMF
  • Products Intro:Purity: 0.99 | Package: 50L;10L
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • TEL: 15502138767
  • Product Name:N,N-Dimethylformamide
  • Products Intro:Purity: 98%(Min,HPLC) | Package: 100g;1kg;5kg,10kg,25kg,50kg
  • Type of Enterprise: Trader
  • Country/Region: CHINA
  • TEL: +86-571-85586718

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