Nifedipine manufacturers and suppliers

Nifedipine suppliers

Properties

Melting point:: 171-175 °C

Boiling point:: 481.08°C (rough estimate)

Density: 1.2109 (rough estimate)

refractive index: 1.5486 (estimate)

storage temp.: 2-8°C

solubility: DMSO: soluble

form: powder

pka: pKa -0.9/>13(DMF,t undefined) (Uncertain)

color: yellow

Water Solubility: <0.1 g/100 mL at 19.5 ºC

Merck: 14,6528

BCS Class: 2

Stability:: Stable for 1 year from date of purchase as supplied. Solutions are not stable and must be used within one working day.

InChIKey: CYCWGQFQPAYBHG-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P301+P312+P330

Hazard Codes: Xn,Xi

Risk Statements: 22-36/37/38

Safety Statements: 26-36

WGK Germany: 1

RTECS: US7975000

HazardClass: IRRITANT

HS Code: 29333990

Toxicity: LD50 in mice, rats (mg/kg): 494, 1022 orally; 4.2, 15.5 i.v. (Vater)

Use

The prototype of this class, nifedipine, has potent peripheralvasodilatory properties. It inhibits the voltage-dependentcalcium channel in the vascular smooth muscle but has littleor no direct depressant effect on the SA or AV nodes, eventhough it inhibits calcium current in normal and isolated cardiactissues. Nifedipine is more effective in patients whoseanginal episodes are caused by coronary vasospasm and isused in the treatment of vasospastic angina as well as classicangina pectoris. Because of its strong vasodilatory properties,it is used in selected patients to treat hypertension.

You can find Nifedipine suppliers, manufacturers, and distributors from countries such as China, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.