Tegafur manufacturers and suppliers

Tegafur suppliers

Properties

Melting point:: 171-173 °C(lit.)

Density: 1.3222 (estimate)

storage temp.: room temp

solubility: DMSO: >50mg/mL

form: Very Fine Crystalline Powder

pka: 7.63±0.10(Predicted)

color: white to off-white

Merck: 14,9112

InChIKey: WFWLQNSHRPWKFK-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS06

Signal word: Danger

Hazard statements: H301+H311+H331

Precautionary statements: P261-P264-P280-P301+P310-P302+P352+P312-P304+P340+P311

Hazard Codes: T

Risk Statements: 23/24/25

Safety Statements: 22-36/37/39-45

RIDADR: UN 2811 6.1/PG 2

WGK Germany: 3

RTECS: YR0450000

HazardClass: 6.1

PackingGroup: II

HS Code: 29349990

Toxicity: LD50 in mice (mg/kg): 900 orally (3 days) (Yasumoto); 750 i.p. (FR 1574684), also reported as 1150 i.p. (Smart)

Use

Tegafur (INN, BAN, USAN) is a prodrug of Fluorouracil (5-FU), an antineoplastic agent used as the treatment of various cancers such as advanced gastric and colorectal cancers. It is a pyrimidine analogue used in combination therapies as an active chemotherapeutic agent in conjunction with Gimeracil and Oteracil, or along with Fluorouracil as Tegafur-uracil. Tegafur is usually given in combination with other drugs that enhance the bioavailability of the 5-FU by blocking the enzyme responsible for its degradation, or serves to limit the toxicity of 5-FU by ensuring high concentrations of 5-FU at a lower dose of tegafur.

You can find Tegafur suppliers, manufacturers, and distributors from countries such as China, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.