Teneligliptin suppliers
Teneligliptin
- CAS:
- 760937-92-6
- MF:
- C22H30N6OS
- MW:
- 426.58
Suppliers by country/region
Company Type
Properties
- Melting point:
- >100°C (dec.)
- Boiling point:
- 663.4±55.0 °C(Predicted)
- Density
- 1.38
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 8.70±0.10(Predicted)
- color
- Off-White
Safety Information
- Symbol(GHS)
GHS07
- Signal word
- Warning
- Hazard statements
- H315-H319
- Precautionary statements
- P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362
Use
Teneligliptin was approved in September 2012 in Japan for the treatment of patients with Type 2 diabetes mellitus (T2DM). Teneligliptin is a member of the dipeptidyl peptidase 4 (DPP-4) inhibitor class of antidiabetes agents. DPP-4 is an enzyme that degrades GLP-1, a 30-amino acid peptide that is secreted in response to food intake. GLP-1 stimulates insulin secretion and inhibits glucagon secretion, which leads to lower levels of plasma glucose. Teneligliptin is one of a growing numbers of DPP-4 inhibitors to be approved worldwide. The discovery of teneligliptin was guided by structure-based design, with a key element being binding of the phenyl group in the S2 pocket, which not only increases potency for DPP-4, but also improves selectivity versus DPP-8 and DPP- 9. Teneligliptin is a potent inhibitor of DPP-4 in the enzyme inhibition assay (IC50=0.37 nM).
142 supplier list of "Teneligliptin"
- Product Name:Teneligliptin
- Products Intro:Purity: 98% Min. | Package: 1G;1KG;100KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 1159983-30-8,89466-59-1,149739-51-5,104901-79-3,10541-83-0
$1000.00/ 1KG
- Product Name:Teneligliptin
- Products Intro:Purity: 99% | Package: 1KG;1000USD
- Company Type: Reagent
- Country/Region: CHINA
- Main Products: Nicotinamide riboside chloride,Curcumin,L(+)-Ascorbic acid,L-Glutamine,Stevioside Basic information
- Product Name:Teneligliptin
- Products Intro:Purity: >98% | Package: 250mg | CustNote: BOC Sciences also provides custom synthesis services for Teneligliptin.
- Company Type: Trader
- Country/Region: UNITED STATES
- Product Name:Teneligliptin
- Products Intro:Purity: 0.98 | Package: 1kg，2kg，5kg，10kg，25kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 2,7-ADA,2,4,6-Trichloroaniline,TRIMETHYLOXONIUM TETRAFLUOROBORATE,Zinc sulfide,5-HEXEN-1-OL
- Product Name:teneligliptin
- Products Intro:Purity: 0.99 | Package: 1kg
- Company Type: Trader
- Country/Region: CHINA
- Product Name:Teneligliptin Hydrobromide Hydrate
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Chlorogenic acid,Tea polyphenol,Acacetin,Gentiopicroside,Jatrorrhizine
- Product Name:Teneligliptin
- Products Intro:Purity: 99% | Package: USP EP CP
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Pharmceutical,Optical Brightening,dyes
![[(2S,4S)-4-[4-(5-methyl-2-phenylpyrazol-3-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone](https://img.chemicalbook.com/CompanyLogo/7a1d34f6-40cf-44fb-85d1-370c0cc719b320210526173348.jpg)
- Product Name:[(2S,4S)-4-[4-(5-methyl-2-phenylpyrazol-3-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone
- Products Intro:Purity: 98% | Package: 1g,10g,25g,500g,1kg
- Company Type: Trader
- Country/Region: CHINA
- Main Products: 528-94-9,AMMONIUM SALICYLATE,Linolenic acid,463-40-1,931-36-2
- Product Name:Teneligliptin
- Products Intro:Purity: 0.99 | Package: 5KG;1KG
- Company Type: Trader
- Country/Region: CHINA
- Main Products: API(Active Pharmaceutical Ingredient),Lab Fine Chemical,Phytochemistry,Cosmetic Raw Materials
- Product Name:Teneligliptin
- Products Intro:Purity: 99% | Package: 100G; 1KG; 5KG; 25KG | CustNote: Pharmaceutical grade
- Company Type: Trader
- Country/Region: CHINA
- Main Products: Shilajit,herb extract,Creatine Monohydrate,Curcumin,Nicotinamide