Isotretinoin manufacturers and suppliers

Isotretinoin suppliers

Properties

Melting point:: 172-175 °C (lit.)

Boiling point:: 381.66°C (rough estimate)

Density: 1.0597 (rough estimate)

refractive index: 1.4800 (estimate)

storage temp.: -20°C

solubility: Practically insoluble in water, soluble in methylene chloride, slightly soluble in ethanol (96 per cent). It is sensitive to air, heat and light, especially in solution. Carry out all operations as rapidly as possible and avoid exposure to actinic light; use freshly prepared solutions.

pka: 4.76±0.33(Predicted)

form: Fine Crystalline Powder

color: Yellow-orange to orange

Water Solubility: insoluble

λmax: 354nm(EtOH)(lit.)

Merck: 14,5228

Stability:: Stable, but probably air and light sensitive. Combustible. Incompatible with strong oxidizing agents.

InChIKey: SHGAZHPCJJPHSC-YCNIQYBTSA-N

Safety Information

Symbol(GHS): GHS07,GHS08

Signal word: Danger

Hazard statements: H315-H319-H335-H360

Precautionary statements: P201-P302+P352-P305+P351+P338-P308+P313

Hazard Codes: T

Risk Statements: 61-36/37/38-20/21/22

Safety Statements: 53-26-36/37/39-45-37/39

WGK Germany: 3

RTECS: VH6440000

TSCA: Yes

HS Code: 29362100

Toxicity: LD50 (20 day) in mice, rats (mg/kg): 904, 901 i.p.; 3389, >4000 orally (Kamm)

Use

Isotretinoin can rapidly and strongly inhibit the cell proliferation and differentiation process of skin glands cells. It has a high effect on severe nodular cystic acne. This product has a high gastrointestinal absorption, but invalid for topical administration. It is used for treating severe acnes which cannot be treated by other drugs. It also has some effects on treating cystic acne, the party of acne, rosacea, ichthyosis, follicular keratosis and pityriasis red hair and other skin diseases.

You can find Isotretinoin suppliers, manufacturers, and distributors from countries such as CHINA, United States and the India here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.