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ChemicalBook >> CAS DataBase List >> Donepezil

Donepezil

Donepezil price.
  • $5 - $2674.98
  • Product name: Donepezil
  • CAS: 120014-06-4
  • MF: C24H29NO3
  • MW: 379.49
  • EINECS:601-651-9
  • MDL Number:MFCD00912833
  • Synonyms:DONEPEZIL;AKOS 226-23;n-1-one ;2-[(1-benzyl-4-piperidyl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one;1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL) METHYL] PIPERIDINE;2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride, hydrate(1:1:1);Donepezil hydrochloride monohydrate;2-[(1-Benzyl-4-piper
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  • AK Scientific
  • American Custom Chemicals Corporation
  • Arctom
  • AvaChem
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • TRC
Package
  • 5mg
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  • 500mg
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  • ManufacturerAK Scientific
  • Product numberJ11266
  • Product descriptionDonepezil
  • Packaging25mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002476
  • Product descriptionARICEPT 95.00%
  • Packaging25MG
  • Price$178.5
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002476
  • Product descriptionARICEPT 95.00%
  • Packaging250MG
  • Price$933.24
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002476
  • Product descriptionARICEPT 95.00%
  • Packaging1G
  • Price$1346.73
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002476
  • Product descriptionARICEPT 95.00%
  • Packaging5G
  • Price$2674.98
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS442986
  • Product description2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one ≥98%
  • Packaging100mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS442986
  • Product description2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one ≥98%
  • Packaging250mg
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS442986
  • Product description2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one ≥98%
  • Packaging1g
  • Price$9
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS442986
  • Product description2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one ≥98%
  • Packaging5g
  • Price$24
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS442986
  • Product description2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one ≥98%
  • Packaging10g
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS442986
  • Product description2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one ≥98%
  • Packaging25g
  • Price$101
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS442986
  • Product description2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one ≥98%
  • Packaging100g
  • Price$362
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1662B
  • Product descriptionDonepezil
  • Packaging25mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1662B
  • Product descriptionDonepezil
  • Packaging100mg
  • Price$139
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1662B
  • Product descriptionDonepezil
  • Packaging1g
  • Price$279
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13245
  • Product descriptionDonepezil ≥95%
  • Packaging10mg
  • Price$32
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J11266 Donepezil 25mg $59 2021-12-16 Buy
American Custom Chemicals Corporation API0002476 ARICEPT 95.00% 25MG $178.5 2021-12-16 Buy
American Custom Chemicals Corporation API0002476 ARICEPT 95.00% 250MG $933.24 2021-12-16 Buy
American Custom Chemicals Corporation API0002476 ARICEPT 95.00% 1G $1346.73 2021-12-16 Buy
American Custom Chemicals Corporation API0002476 ARICEPT 95.00% 5G $2674.98 2021-12-16 Buy
Arctom AS442986 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one ≥98% 100mg $5 2021-12-16 Buy
Arctom AS442986 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one ≥98% 250mg $7 2021-12-16 Buy
Arctom AS442986 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one ≥98% 1g $9 2021-12-16 Buy
Arctom AS442986 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one ≥98% 5g $24 2021-12-16 Buy
Arctom AS442986 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one ≥98% 10g $42 2021-12-16 Buy
Arctom AS442986 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one ≥98% 25g $101 2021-12-16 Buy
Arctom AS442986 2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one ≥98% 100g $362 2021-12-16 Buy
AvaChem 1662B Donepezil 25mg $59 2021-12-16 Buy
AvaChem 1662B Donepezil 100mg $139 2021-12-16 Buy
AvaChem 1662B Donepezil 1g $279 2021-12-16 Buy
Cayman Chemical 13245 Donepezil ≥95% 10mg $32 2024-03-01 Buy

Properties

Melting point :207°C
Boiling point :527.9±50.0 °C(Predicted)
Density :1.141±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
solubility :Acetone (Slightly), Chloroform (Slightly)
form :Solid
pka :8.84±0.10(Predicted)
color :White to Off-White
Water Solubility :2.931 mg/L
CAS DataBase Reference :120014-06-4(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Donepezil is a reversible acetylcholinesterase inhibitor that readily crosses the blood-brain barrier to reduce the breakdown of acetylcholine. It has a half-life in circulation of about 70 hours. As acetylcholine modulates plasticity, excitability, and arousal in the central nervous system, donepezil is commonly used in the treatment of Alzheimer’s disease to improve cognition, memory, and behavior. In this way, it is intended to prevent or reverse dementia. Studies on these effects have been equivocal, indicating that more research into the therapeutic potential of donepezil is warranted.