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ChemicalBook >> CAS DataBase List >> Abiraterone acetate

Abiraterone acetate

Abiraterone acetate price.
  • $28 - $1730
  • Product name: Abiraterone acetate
  • CAS: 154229-18-2
  • MF: C26H33NO2
  • MW: 391.55
  • EINECS:620-314-7
  • MDL Number:MFCD00934213
  • Synonyms:Abiraterone acetate 99.5%;Abiraterone acetate(CB7630);3β-acetoxy-17-(3-pyridyl)androsta-5,16-diene;2-((3S,8R,9S,10R,13S,14S)-10,13-diMethyl-17-(pyridin-3-yl)-2,3,4,7,8,9,10,11,12,13,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl)acetate;Abiraterone acetate ester;Androsta-5,16-dien-3-ol,17-(3-pyridinyl)-, acetate (ester), (3b)-;Abiraterone Acetate impurity;(3β)-17-(3-pyridinyl) androsta-5,16-dien-3-yl acetate
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  • AK Scientific
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  • ManufacturerAK Scientific
  • Product numberJ50777
  • Product descriptionAbiraterone acetate
  • Packaging25g
  • Price$1592
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA8202
  • Product descriptionAbiraterone acetate
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA8202
  • Product descriptionAbiraterone acetate
  • Packaging5mg
  • Price$45
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA8202
  • Product descriptionAbiraterone acetate
  • Packaging50mg
  • Price$179
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberCFN90022
  • Product descriptionAbiraterone acetate ≥98%
  • Packaging20mg
  • Price$168
  • Updated2021-12-16
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  • ManufacturerAxon Medchem
  • Product numberAxon1874
  • Product descriptionAbirateroneacetate-CB7630|JNJ212082 100%
  • Packaging2x50mg
  • Price$440
  • Updated2021-12-16
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  • ManufacturerAxon Medchem
  • Product numberAxon1874
  • Product descriptionAbirateroneacetate-CB7630|JNJ212082 100%
  • Packaging50mg
  • Price$297
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberBA164133
  • Product descriptionAbiraterone acetate
  • Packaging10mg
  • Price$54
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFA16106
  • Product descriptionAbiraterone acetate
  • Packaging250mg
  • Price$62.5
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberBA164133
  • Product descriptionAbiraterone acetate
  • Packaging100mg
  • Price$86
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFA16106
  • Product descriptionAbiraterone acetate
  • Packaging500mg
  • Price$100
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFA16106
  • Product descriptionAbiraterone acetate
  • Packaging1g
  • Price$150
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFA16106
  • Product descriptionAbiraterone acetate
  • Packaging2g
  • Price$250
  • Updated2021-12-16
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  • ManufacturerBiosynth Carbosynth
  • Product numberFA16106
  • Product descriptionAbiraterone acetate
  • Packaging5G
  • Price$500
  • Updated2021-12-16
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  • ManufacturerCayman Chemical
  • Product number15148
  • Product descriptionAbiraterone Acetate ≥98%
  • Packaging5mg
  • Price$121
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number15148
  • Product descriptionAbiraterone Acetate ≥98%
  • Packaging10mg
  • Price$183
  • Updated2024-03-01
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Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J50777 Abiraterone acetate 25g $1592 2021-12-16 Buy
ApexBio Technology A8202 Abiraterone acetate 1unit $28 2021-12-16 Buy
ApexBio Technology A8202 Abiraterone acetate 5mg $45 2021-12-16 Buy
ApexBio Technology A8202 Abiraterone acetate 50mg $179 2021-12-16 Buy
Arctom CFN90022 Abiraterone acetate ≥98% 20mg $168 2021-12-16 Buy
Axon Medchem Axon1874 Abirateroneacetate-CB7630|JNJ212082 100% 2x50mg $440 2021-12-16 Buy
Axon Medchem Axon1874 Abirateroneacetate-CB7630|JNJ212082 100% 50mg $297 2021-12-16 Buy
Biosynth Carbosynth BA164133 Abiraterone acetate 10mg $54 2021-12-16 Buy
Biosynth Carbosynth FA16106 Abiraterone acetate 250mg $62.5 2021-12-16 Buy
Biosynth Carbosynth BA164133 Abiraterone acetate 100mg $86 2021-12-16 Buy
Biosynth Carbosynth FA16106 Abiraterone acetate 500mg $100 2021-12-16 Buy
Biosynth Carbosynth FA16106 Abiraterone acetate 1g $150 2021-12-16 Buy
Biosynth Carbosynth FA16106 Abiraterone acetate 2g $250 2021-12-16 Buy
Biosynth Carbosynth FA16106 Abiraterone acetate 5G $500 2021-12-16 Buy
Cayman Chemical 15148 Abiraterone Acetate ≥98% 5mg $121 2024-03-01 Buy
Cayman Chemical 15148 Abiraterone Acetate ≥98% 10mg $183 2024-03-01 Buy

Properties

Melting point :127-130°C
Boiling point :506.7±50.0 °C(Predicted)
Density :1.14±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :Chloroform (Slightly), DMSO (Sparingly), Methanol (Sparingly)
pka :5.31±0.12(Predicted)
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

The cytochrome P450 (CYP) isoform CYP17A1 is also known as steroid 17α-hydroxylase/17,20 lyase because it catalyzes both 17α-hydroxylase and 17,20 lyase reactions in the synthesis of steroids, including androgens, estrogens, glucocorticoids, and mineralocorticoids. Abiraterone acetate blocks CYP17A1 by potently inhibiting both the 17α-hydroxylase and the 17,20 lyase activities (IC50 = 18 and 17 nM, respectively). In mice as well as men, it essentially eliminates plasma testosterone while producing a 3- to 4-fold increase in plasma luteinizing hormone. It improves radiographic progression-free survival and significantly delays decline in human metastatic castration-resistant prostate cancer.