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ChemicalBook >> CAS DataBase List >> Protocatechuic acid

Protocatechuic acid

Protocatechuic acid price.
  • $10 - $700
  • Product name: Protocatechuic acid
  • CAS: 99-50-3
  • MF: C7H6O4
  • MW: 154.12
  • EINECS:202-760-0
  • MDL Number:MFCD00002509
  • Synonyms:3,4-Dihydroxybenzoic acid >=97.0% (T);Carbohydroquinonic acid;Hypogallic acid;3,4-Dihydroxybenzoic acid, >=99%;Benzoic acid, 3,4-dihydroxy-;PROTOCATECHUIC ACID(RG);3,4-DIHYDROXYBENZOIC ACID / PROTOCATECHUIC ACID;4-Carboxy-1,2-dihydroxybenzene
Price46 Properties Safety Information Description
46 prices
Selected condition：
Brand
  • AK Scientific
  • Alfa Aesar
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Crysdot
  • DC Chemicals
  • Frontier Specialty Chemicals
  • JR MediChem
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • SynQuest Laboratories
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 10mM(in 1mL DMSO)
  • 5mg
  • 20mg
  • 50mg
  • 100MG
  • 200mg
  • 1000mg
  • 1g
  • 5g
  • 25g
  • 50g
  • 100g
  • 250g
  • 500g
  • 1000g
  • 1kg
  • 2Kg
  • ManufacturerAK Scientific
  • Product numberJ91727
  • Product description3,4-Dihydroxybenzoic Acid
  • Packaging5g
  • Price$10
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberB24016
  • Product description3,4-Dihydroxybenzoic acid, 97%
  • Packaging25g
  • Price$61.5
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberB24016
  • Product description3,4-Dihydroxybenzoic acid, 97%
  • Packaging100g
  • Price$176
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberB24016
  • Product description3,4-Dihydroxybenzoic acid, 97%
  • Packaging500g
  • Price$570.65
  • Updated2024-03-01
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN2466
  • Product description3,4-Dihydroxybenzoic Acid
  • Packaging200mg
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN2466
  • Product description3,4-Dihydroxybenzoic Acid
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberN2466
  • Product description3,4-Dihydroxybenzoic Acid
  • Packaging1g
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR52125
  • Product description3,4-Dihydroxybenzoic Acid
  • Packaging25g
  • Price$57
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR52125
  • Product description3,4-Dihydroxybenzoic Acid
  • Packaging100g
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR52125
  • Product description3,4-Dihydroxybenzoic Acid
  • Packaging500g
  • Price$360
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN97568
  • Product description3,4-Dihydroxybenzoic Acid
  • Packaging20mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3289
  • Product descriptionProtocatechuic Acid
  • Packaging5mg
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number3289
  • Product descriptionProtocatechuic Acid
  • Packaging20mg
  • Price$119
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb594219
  • Product descriptionProtocatechuic Acid
  • Packaging20mg
  • Price$153
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb594219
  • Product descriptionProtocatechuic Acid
  • Packaging1000mg
  • Price$221
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb105706
  • Product description3,4-Dihydroxybenzoic acid >98%,Standard References Grade
  • Packaging20mg
  • Price$569.5
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J91727 3,4-Dihydroxybenzoic Acid 5g $10 2021-12-16 Buy
Alfa Aesar B24016 3,4-Dihydroxybenzoic acid, 97% 25g $61.5 2024-03-01 Buy
Alfa Aesar B24016 3,4-Dihydroxybenzoic acid, 97% 100g $176 2024-03-01 Buy
Alfa Aesar B24016 3,4-Dihydroxybenzoic acid, 97% 500g $570.65 2024-03-01 Buy
ApexBio Technology N2466 3,4-Dihydroxybenzoic Acid 200mg $42 2021-12-16 Buy
ApexBio Technology N2466 3,4-Dihydroxybenzoic Acid 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology N2466 3,4-Dihydroxybenzoic Acid 1g $60 2021-12-16 Buy
Apolloscientific OR52125 3,4-Dihydroxybenzoic Acid 25g $57 2021-12-16 Buy
Apolloscientific OR52125 3,4-Dihydroxybenzoic Acid 100g $96 2021-12-16 Buy
Apolloscientific OR52125 3,4-Dihydroxybenzoic Acid 500g $360 2021-12-16 Buy
Arctom CFN97568 3,4-Dihydroxybenzoic Acid 20mg $30 2021-12-16 Buy
AvaChem 3289 Protocatechuic Acid 5mg $59 2021-12-16 Buy
AvaChem 3289 Protocatechuic Acid 20mg $119 2021-12-16 Buy
Biorbyt Ltd orb594219 Protocatechuic Acid 20mg $153 2021-12-16 Buy
Biorbyt Ltd orb594219 Protocatechuic Acid 1000mg $221 2021-12-16 Buy
Biorbyt Ltd orb105706 3,4-Dihydroxybenzoic acid >98%,Standard References Grade 20mg $569.5 2021-12-16 Buy
Next Last

Properties

Melting point :197-200 °C (dec.) (lit.)
Boiling point :237.46°C (rough estimate)
Density :1.54
refractive index :1.6400 (estimate)
FEMA :4430 | 3,4-DIHYDROXYBENZOIC ACID
storage temp. :Store below +30°C.
solubility :20g/l
pka :4.48(at 25℃)
form :Fine Crystalline Powder
color :Beige to brown
PH :3.78(1 mM solution);3.25(10 mM solution);2.74(100 mM solution)
Odor :at 100.00 %. mild phenolic balsamic
Odor Type :phenolic
Water Solubility :Soluble in hot alcohol and ether. Slightly soluble in water.
Sensitive :Air Sensitive
Merck :14,7894
BRN :1448841
Stability :Stable. Incompatible with strong oxidizing agents, strong bases.
InChIKey :YQUVCSBJEUQKSH-UHFFFAOYSA-N
LogP :1.16
CAS DataBase Reference :99-50-3(CAS DataBase Reference)
EPA Substance Registry System :Protocatechuic acid (99-50-3)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Protocatechuic acid (PCA) is a dihydroxybenzoic acid phenolic compound found in many edible and medicinal plants. It is a major metabolite of antioxidant polyphenols found in green tea and demonstrates free radical scavenging capability in a 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity assay (IC50 = 16.3 μM). It is thought to possess anti-inflammatory, antihyperglycemic, neuroprotective, and anticancer activities. Dietary administration of PCA dose dependently inhibits in vitro chemical carcinogenesis and exerts pro-apoptotic and anti-proliferative effects in different tissues. In studies of tumor cell migration and invasion using mouse melanoma B16/F10 cells, PCA at 0.1-2 mM down-regulated the Ras/Akt/NF-κB pathway by targeting RhoB activation, leading to a reduction of MMP-mediated activity.

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Suppliers and manufacturers

Jiangxi Chiyan Biopharmaceutical Technology Co.,Ltd.
Huanfu Industrial Co.，（Shanghai）Ltd.
Capot Chemical Co.,Ltd.
Shanghai Daken Advanced Materials Co.,Ltd
Dalian Richfortune Chemicals Co., Ltd
Henan Tianfu Chemical Co.,Ltd.
Nanjing ChemLin Chemical Industry Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
Anqing Chico Pharmaceutical Co., Ltd.
Shanghai Zheyan Biotech Co., Ltd.