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ChemicalBook >> CAS DataBase List >> 4-CHLOROBENZO[F]ISOQUINOLINE

4-CHLOROBENZO[F]ISOQUINOLINE

4-CHLOROBENZO[F]ISOQUINOLINE price.
  • $180 - $711
  • Product name: 4-CHLOROBENZO[F]ISOQUINOLINE
  • CAS: 32081-28-0
  • MF: C13H8ClN
  • MW: 213.66
  • EINECS:
  • MDL Number:MFCD02179769
  • Synonyms:4-CHLOROBENZO[F]ISOQUINOLINE;CBIQ;Benz[f]isoquinoline, 4-chloro-;CBIQ >=98% (HPLC), solid
3 prices
Selected condition:
Brand
  • American Custom Chemicals Corporation
  • Sigma-Aldrich
Package
  • 5mg
  • 25mg
  • 0.1G
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0008630
  • Product description4-CHLOROBENZO[F]ISOQUINOLINE 95.00%
  • Packaging0.1G
  • Price$329
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberC6617
  • Product descriptionCBIQ ≥98% (HPLC), solid
  • Packaging5mg
  • Price$180
  • Updated2025-07-31
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberC6617
  • Product descriptionCBIQ ≥98% (HPLC), solid
  • Packaging25mg
  • Price$711
  • Updated2025-07-31
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0008630 4-CHLOROBENZO[F]ISOQUINOLINE 95.00% 0.1G $329 2021-12-16 Buy
Sigma-Aldrich C6617 CBIQ ≥98% (HPLC), solid 5mg $180 2025-07-31 Buy
Sigma-Aldrich C6617 CBIQ ≥98% (HPLC), solid 25mg $711 2025-07-31 Buy

Properties

Boiling point :400.3±18.0 °C(Predicted)
Density :1.312±0.06 g/cm3(Predicted)
solubility :DMSO: soluble15mg/mL
pka :3.21±0.30(Predicted)
form :solid
color :off-white

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.

Description

An activator of the cystic fibrosis transmembrane conductance regulator (CFTR) and the intermediate-conductance calcium-sensitive K+ channel (KCNN4). May act as a novel tool for a new ion channel. First activator of F508 CFTR, the mutant form of CFTR chloride channel present in 75% of cystic fibrosis patients. Other benzoquinolines act at the normal CFTR but not at F508 CFTR. CBIQ also activates KCNN4, which hyperpolarizes airway epithelial cells to promote anion flux, a further benefit in cystic fibrosis.

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