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ChemicalBook >> CAS DataBase List >> 6-(4-FLUOROPHENYL)-2,3-DIHYDRO-5-(4-PYRIDINYL)IMIDAZO[2,1-B]THIAZOLE DIHYDROCHLORIDE

6-(4-FLUOROPHENYL)-2,3-DIHYDRO-5-(4-PYRIDINYL)IMIDAZO[2,1-B]THIAZOLE DIHYDROCHLORIDE

6-(4-FLUOROPHENYL)-2,3-DIHYDRO-5-(4-PYRIDINYL)IMIDAZO[2,1-B]THIAZOLE DIHYDROCHLORIDE price.
  • $36 - $4327
  • Product name: 6-(4-FLUOROPHENYL)-2,3-DIHYDRO-5-(4-PYRIDINYL)IMIDAZO[2,1-B]THIAZOLE DIHYDROCHLORIDE
  • CAS: 72873-74-6
  • MF: C16H12FN3S
  • MW: 297.35
  • EINECS:
  • MDL Number:MFCD00869367
  • Synonyms:6-(4-FLUOROPHENYL)-5-(4-PYRIDYL)-2,3-DIHYDROIMIDAZO[2,1-B]-THIAZOLE;6-(4-FLUOROPHENYL)-2,3-DIHYDRO-5-(4-PRIDYL)IMIDAZO-[2,1,B]-THAIZOLE;6-(4-FLUOROPHENYL)-2,3-DIHYDRO-5-(4-PYRIDINYL)IMIDAZO[2,1-B]THIAZOLE DIHYDROCHLORIDE;6-(4-FLUOROPHENYL)-2,3-DIHYDRO-5-(4-PYRIDYL)IMIDAZO[2,1-B]THIAZOLE;SKF-86002;SKF 86002 DIHYDROCHLORIDE;6-(4-fluorophenyl)-2,3-dihydro-5-(4-pyridinyl)imidazo(2,1-b)thiazole;4-(4-Pyridyl)-5-(4-fluorophenyl)-2,3-dihydro-1-thia-3a,6-diazapentalene
32 prices
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Arctom
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 2mg
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  • 25mg
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  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product number1314AC
  • Product description6-(4-Fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b]thiazole
  • Packaging100mg
  • Price$278
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA251928
  • Product descriptionSKF-86002 98+%
  • Packaging2mg
  • Price$73
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA251928
  • Product descriptionSKF-86002 98+%
  • Packaging5mg
  • Price$116
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA251928
  • Product descriptionSKF-86002 98+%
  • Packaging10mg
  • Price$174
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA251928
  • Product descriptionSKF-86002 98+%
  • Packaging50mg
  • Price$392
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA251928
  • Product descriptionSKF-86002 98+%
  • Packaging100mg
  • Price$509
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA251928
  • Product descriptionSKF-86002 98+%
  • Packaging1g
  • Price$4327
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000233
  • Product descriptionSKF-86002 95.00%
  • Packaging10MG
  • Price$709.46
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000233
  • Product descriptionSKF-86002 95.00%
  • Packaging50MG
  • Price$1267.33
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS494860
  • Product descriptionSKF-86002 ≥98%
  • Packaging2mg
  • Price$42
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS494860
  • Product descriptionSKF-86002 ≥98%
  • Packaging5mg
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS494860
  • Product descriptionSKF-86002 ≥98%
  • Packaging10mg
  • Price$69
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS494860
  • Product descriptionSKF-86002 ≥98%
  • Packaging50mg
  • Price$118
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS494860
  • Product descriptionSKF-86002 ≥98%
  • Packaging100mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS494860
  • Product descriptionSKF-86002 ≥98%
  • Packaging250mg
  • Price$316
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS494860
  • Product descriptionSKF-86002 ≥98%
  • Packaging1g
  • Price$788
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 1314AC 6-(4-Fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b]thiazole 100mg $278 2021-12-16 Buy
Ambeed A251928 SKF-86002 98+% 2mg $73 2021-12-16 Buy
Ambeed A251928 SKF-86002 98+% 5mg $116 2021-12-16 Buy
Ambeed A251928 SKF-86002 98+% 10mg $174 2021-12-16 Buy
Ambeed A251928 SKF-86002 98+% 50mg $392 2021-12-16 Buy
Ambeed A251928 SKF-86002 98+% 100mg $509 2021-12-16 Buy
Ambeed A251928 SKF-86002 98+% 1g $4327 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000233 SKF-86002 95.00% 10MG $709.46 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000233 SKF-86002 95.00% 50MG $1267.33 2021-12-16 Buy
Arctom AS494860 SKF-86002 ≥98% 2mg $42 2021-12-16 Buy
Arctom AS494860 SKF-86002 ≥98% 5mg $53 2021-12-16 Buy
Arctom AS494860 SKF-86002 ≥98% 10mg $69 2021-12-16 Buy
Arctom AS494860 SKF-86002 ≥98% 50mg $118 2021-12-16 Buy
Arctom AS494860 SKF-86002 ≥98% 100mg $160 2021-12-16 Buy
Arctom AS494860 SKF-86002 ≥98% 250mg $316 2021-12-16 Buy
Arctom AS494860 SKF-86002 ≥98% 1g $788 2021-12-16 Buy

Properties

Melting point :189-190 °C(lit.)
Boiling point :476.1±55.0 °C(Predicted)
Density :1.39±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,2-8°C
solubility :DMSO: 9 mg/mL, soluble
form :solid
pka :4.36±0.10(Predicted)
color :off-white
InChIKey :YOELZIQOLWZLQC-UHFFFAOYSA-N

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H227 Combustible liquid Flammable liquids Category 4 Warning P210, P280, P370+P378, P403+P235,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.

Description

SKF 86002 is a bicyclic imidazole that specifically inhibits p38 MAP kinase, and is also described as a cytokine-suppressant and an anti-inflammatory compound. SKF 86002 has been shown to inhibit Cox (cyclooxygenase) activity and 5-LO (5-lipoxygenase). Osteoblastic cell studies report that SKF 86002 inhibits the production of IL-6. SKF 86002 has been shown to block the activation of TNF-translation and potently inhibit IL-1.

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