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ChemicalBook >> CAS DataBase List >> 18β-Glycyrrhetinic Acid

18β-Glycyrrhetinic Acid

18β-Glycyrrhetinic Acid price.
  • $19.8 - $3176.25
  • Product name: 18β-Glycyrrhetinic Acid
  • CAS: 471-53-4
  • MF: C30H46O4
  • MW: 470.69
  • EINECS:207-444-6
  • MDL Number:MFCD00003706
  • Synonyms:Enoxolone, 3β-Hydroxy-11-oxo-18β,20β-olean-12-en-29-oic acid;Aloe Vera, Freeze Dried Powder;18-β-Glycyrrhetinic acid, 98+%;18-beta-glycyrrheticacid ;Olean-12-en-29-oic acid, 3-hydroxy-11-oxo-, (3b,20b)-;(20S)-3β-Hydroxy-11-oxo-5α-olean-12-en-29-oic acid;GLYCYRRHETINIC ACID, 18B-(P);Glycyrrhetinic acid ,98%
Price43 Properties Safety Information Description
43 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 10mg
  • e0180500
  • 5MG
  • 20mg
  • 25mg
  • 1g
  • 1000mg
  • 5g
  • 10G
  • 25g
  • 50g
  • 100g
  • 250g
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product numberC425
  • Product descriptionEnoxolone
  • Packaging5g
  • Price$27
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10770
  • Product descriptionEnoxolone
  • Packaging25mg
  • Price$39
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10770
  • Product descriptionEnoxolone
  • Packaging1g
  • Price$149
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCCH0007789
  • Product description(2S,4AS,6AS,6BR,8AR,10S,12AS,12BR,14BR)-10-HYDROXY-2,4A,6A,6B,9,9,12A-HEPTAMETHYL-13-OXO-1,2,3,4,4A,5,6,6A,6B,7,8,8A,9,10,11,12,12A,12B,13,14B-ICOSAHYDROPICENE-2-CARBOXYLIC ACID 95.00%
  • Packaging1G
  • Price$131.25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPXT0005604
  • Product description18-BETA GLYCYRRHETINIC ACID 95.00%
  • Packaging5MG
  • Price$458.56
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002854
  • Product descriptionGLYCYRRHETINIC ACID 95.00%
  • Packaging1G
  • Price$704.55
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002854
  • Product descriptionGLYCYRRHETINIC ACID 95.00%
  • Packaging10G
  • Price$2055.9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCCH0007789
  • Product description(2S,4AS,6AS,6BR,8AR,10S,12AS,12BR,14BR)-10-HYDROXY-2,4A,6A,6B,9,9,12A-HEPTAMETHYL-13-OXO-1,2,3,4,4A,5,6,6A,6B,7,8,8A,9,10,11,12,12A,12B,13,14B-ICOSAHYDROPICENE-2-CARBOXYLIC ACID 95.00%
  • Packaging5G
  • Price$2252.25
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberCCH0007789
  • Product description(2S,4AS,6AS,6BR,8AR,10S,12AS,12BR,14BR)-10-HYDROXY-2,4A,6A,6B,9,9,12A-HEPTAMETHYL-13-OXO-1,2,3,4,4A,5,6,6A,6B,7,8,8A,9,10,11,12,12A,12B,13,14B-ICOSAHYDROPICENE-2-CARBOXYLIC ACID 95.00%
  • Packaging10G
  • Price$3176.25
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5986
  • Product descriptionEnoxolone
  • Packaging1g
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5986
  • Product descriptionEnoxolone
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB5986
  • Product descriptionEnoxolone
  • Packaging5g
  • Price$85
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN99152
  • Product descriptionGlycyrrhetinicacid ≥98%
  • Packaging20mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSY075768
  • Product description(2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-Hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylicAcid ≥98%
  • Packaging10mg
  • Price$40.91
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1106
  • Product description18-Beta-Glycyrrhetinic Acid
  • Packaging1g
  • Price$59
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb593978
  • Product descriptionGlycyrrhetinic acid
  • Packaging20mg
  • Price$153
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific C425 Enoxolone 5g $27 2021-12-16 Buy
AK Scientific J10770 Enoxolone 25mg $39 2021-12-16 Buy
AK Scientific J10770 Enoxolone 1g $149 2021-12-16 Buy
American Custom Chemicals Corporation CCH0007789 (2S,4AS,6AS,6BR,8AR,10S,12AS,12BR,14BR)-10-HYDROXY-2,4A,6A,6B,9,9,12A-HEPTAMETHYL-13-OXO-1,2,3,4,4A,5,6,6A,6B,7,8,8A,9,10,11,12,12A,12B,13,14B-ICOSAHYDROPICENE-2-CARBOXYLIC ACID 95.00% 1G $131.25 2021-12-16 Buy
American Custom Chemicals Corporation PXT0005604 18-BETA GLYCYRRHETINIC ACID 95.00% 5MG $458.56 2021-12-16 Buy
American Custom Chemicals Corporation API0002854 GLYCYRRHETINIC ACID 95.00% 1G $704.55 2021-12-16 Buy
American Custom Chemicals Corporation API0002854 GLYCYRRHETINIC ACID 95.00% 10G $2055.9 2021-12-16 Buy
American Custom Chemicals Corporation CCH0007789 (2S,4AS,6AS,6BR,8AR,10S,12AS,12BR,14BR)-10-HYDROXY-2,4A,6A,6B,9,9,12A-HEPTAMETHYL-13-OXO-1,2,3,4,4A,5,6,6A,6B,7,8,8A,9,10,11,12,12A,12B,13,14B-ICOSAHYDROPICENE-2-CARBOXYLIC ACID 95.00% 5G $2252.25 2021-12-16 Buy
American Custom Chemicals Corporation CCH0007789 (2S,4AS,6AS,6BR,8AR,10S,12AS,12BR,14BR)-10-HYDROXY-2,4A,6A,6B,9,9,12A-HEPTAMETHYL-13-OXO-1,2,3,4,4A,5,6,6A,6B,7,8,8A,9,10,11,12,12A,12B,13,14B-ICOSAHYDROPICENE-2-CARBOXYLIC ACID 95.00% 10G $3176.25 2021-12-16 Buy
ApexBio Technology B5986 Enoxolone 1g $50 2021-12-16 Buy
ApexBio Technology B5986 Enoxolone 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology B5986 Enoxolone 5g $85 2021-12-16 Buy
Arctom CFN99152 Glycyrrhetinicacid ≥98% 20mg $30 2021-12-16 Buy
Arctom SY075768 (2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-Hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylicAcid ≥98% 10mg $40.91 2021-12-16 Buy
AvaChem 1106 18-Beta-Glycyrrhetinic Acid 1g $59 2021-12-16 Buy
Biorbyt Ltd orb593978 Glycyrrhetinic acid 20mg $153 2021-12-16 Buy
Next Last

Properties

Melting point :292-295 °C(lit.)
alpha :165 º (c=1, CHCl3,on dry ba)
Boiling point :492.11°C (rough estimate)
Density :0.9967 (rough estimate)
vapor pressure :10-220Pa at 20-50℃
refractive index :162 ° (C=1, MeOH)
storage temp. :2-8°C
solubility :Practically insoluble in water, soluble in ethanol, sparingly soluble in methylene chloride.
pka :pKa 5.56±0.1 (Uncertain)
form :Crystalline Powder
color :White to off-white
optical activity :[α]22/D +170.0°, c = 1 in chloroform
Water Solubility :SOLUBLE IN ACETIC ACID
Merck :14,3590
BRN :2229654
LogP :4.5 at 20℃
CAS DataBase Reference :471-53-4(CAS DataBase Reference)
EPA Substance Registry System :Enoxolone (471-53-4)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

β-Glycyrrhetinic acid is a major metabolite of glycyrrhizin, one of the main constituents of licorice. Both β-glycyrrhetinic acid and glycyrrhizin have been shown to exhibit antiulcerative, anti-inflammatory, and immunomodulatory properties. β-Glycyrrhetinic acid is an inhibitor of the complement pathway (IC50 = 35 μM). At 100 mg/kg/day, β-glycyrrhetinic acid is protective against diabetes complications by reducing lipid peroxidation and increasing antioxidant activity in diabetic rats. β-Glycyrrhetinic acid inhibits mammalian DNA polymerases α, γ, κ, and λ with IC50 values of 16.1, 19.3, 15.8, and 13.7 μM, respectively. At 100-200 μM, β-glycyrrhetinic acid suppresses LPS-induced TNF-α production and NF-κB activation in mouse macrophages.

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Suppliers and manufacturers

Henan Tengmao Chemical Technology Co. LTD
18β-Glycyrrhetinic Acid
$90.00/kilogram
18β-Glycyrrhetinic Acid CAS:471-53-4
Shaanxi Haibo Biotechnology Co., Ltd
Aloe vera freeze-dried powder
$0.00 /1KG
Aloe vera freeze-dried powder CAS:
career henan chemical co
Enoxolone
$1.00 /1KG
Enoxolone CAS:471-53-4
Shanghai Daken Advanced Materials Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Shanghai Time Chemicals CO., Ltd.
Hangzhou FandaChem Co.,Ltd.
Shanghai Zheyan Biotech Co., Ltd.
SHANDONG ZHI SHANG CHEMICAL CO.LTD
Chengdu Biopurify Phytochemicals Ltd.