Welcome to chemicalbook!
400-158-6606

Get started now

or
My Account
Buyers
Inquiry management
Suppliers
Quotation management
ChemicalBook >> CAS DataBase List >> Promethazine hydrochloride

Promethazine hydrochloride

Promethazine hydrochloride  price.
  • $15 - $348
  • Product name: Promethazine hydrochloride
  • CAS: 58-33-3
  • MF: C17H21ClN2S
  • MW: 320.88
  • EINECS:200-375-2
  • MDL Number:MFCD00012652
  • Synonyms:10-(2-dimethylaminopropyl)phenothiazinehydrochloride ;10-(3-dimethylaminoisopropyl)phenothiazinehydrochloride ;atosil ;diprasine ;diprazin ;dorme ;fellozine ;fenergan
17 prices
Selected condition:

Brand

  • Cayman Chemical
  • Sigma-Aldrich
  • TCI Chemical

Package

  • 044-25mg
  • 1mg
  • y0000797
  • 5mg
  • 111-1ml
  • 10mg
  • 250mg
  • 500mg
  • 1g
  • 10g
  • 25g
  • 100g
  • p3400000
  • 50g
  • ManufacturerCayman Chemical
  • Product number22450
  • Product descriptionPromethazine (hydrochloride) ≥98%
  • Packaging5mg
  • Price$15
  • Updated2018-11-19
  • Buy
  • ManufacturerCayman Chemical
  • Product number21331
  • Product descriptionPromethazine (hydrochloride) (CRM)
  • Packaging1mg
  • Price$19
  • Updated2018-11-19
  • Buy
  • ManufacturerCayman Chemical
  • Product number16478
  • Product descriptionPromethazine (hydrochloride) ≥95%
  • Packaging10g
  • Price$25
  • Updated2018-11-13
  • Buy
  • ManufacturerCayman Chemical
  • Product number22450
  • Product descriptionPromethazine (hydrochloride) ≥98%
  • Packaging10mg
  • Price$27
  • Updated2018-11-19
  • Buy
  • ManufacturerCayman Chemical
  • Product number16478
  • Product descriptionPromethazine (hydrochloride) ≥95%
  • Packaging25g
  • Price$41
  • Updated2018-11-13
  • Buy
  • ManufacturerCayman Chemical
  • Product number16478
  • Product descriptionPromethazine (hydrochloride) ≥95%
  • Packaging50g
  • Price$75
  • Updated2018-11-13
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberP4651
  • Product descriptionPromethazine hydrochloride
  • Packaging100g
  • Price$175
  • Updated2018-11-13
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberP3400000
  • Product descriptionPromethazine hydrochloride European Pharmacopoeia (EP) Reference Standard
  • Packagingp3400000
  • Price$179
  • Updated2018-11-23
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberY0000797
  • Product descriptionPromethazine for peak identification European Pharmacopoeia (EP) Reference Standard
  • Packagingy0000797
  • Price$179
  • Updated2018-11-23
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number1570009
  • Product descriptionPromethazine hydrochloride United States Pharmacopeia (USP) Reference Standard
  • Packaging500mg
  • Price$348
  • Updated2018-11-13
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number46682
  • Product descriptionPromethazine hydrochloride VETRANAL , analytical standard
  • Packaging250mg
  • Price$45.5
  • Updated2018-11-13
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberP-044
  • Product descriptionPromethazine hydrochloride vial of 25 mg, certified reference material
  • Packaging044-25mg
  • Price$52
  • Updated2018-11-13
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberP-111
  • Product descriptionPromethazine hydrochloride 1.0 mg/mL (1% 1 M HCl in Methanol (as free base)), ampule of 1 mL, certified reference material
  • Packaging111-1ml
  • Price$52
  • Updated2018-11-13
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberP4651
  • Product descriptionPromethazine hydrochloride
  • Packaging25g
  • Price$52.5
  • Updated2018-11-13
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberPHR1467
  • Product descriptionPromethazine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material
  • Packaging1g
  • Price$66.9
  • Updated2018-11-20
  • Buy
  • ManufacturerTCI Chemical
  • Product numberP2029
  • Product descriptionPromethazine Hydrochloride >98.0%(HPLC)(T)
  • Packaging25g
  • Price$49
  • Updated2018-11-22
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 22450 Promethazine (hydrochloride) ≥98% 5mg $15 2018-11-19 Buy
Cayman Chemical 21331 Promethazine (hydrochloride) (CRM) 1mg $19 2018-11-19 Buy
Cayman Chemical 16478 Promethazine (hydrochloride) ≥95% 10g $25 2018-11-13 Buy
Cayman Chemical 22450 Promethazine (hydrochloride) ≥98% 10mg $27 2018-11-19 Buy
Cayman Chemical 16478 Promethazine (hydrochloride) ≥95% 25g $41 2018-11-13 Buy
Cayman Chemical 16478 Promethazine (hydrochloride) ≥95% 50g $75 2018-11-13 Buy
Sigma-Aldrich P4651 Promethazine hydrochloride 100g $175 2018-11-13 Buy
Sigma-Aldrich P3400000 Promethazine hydrochloride European Pharmacopoeia (EP) Reference Standard p3400000 $179 2018-11-23 Buy
Sigma-Aldrich Y0000797 Promethazine for peak identification European Pharmacopoeia (EP) Reference Standard y0000797 $179 2018-11-23 Buy
Sigma-Aldrich 1570009 Promethazine hydrochloride United States Pharmacopeia (USP) Reference Standard 500mg $348 2018-11-13 Buy
Sigma-Aldrich 46682 Promethazine hydrochloride VETRANAL , analytical standard 250mg $45.5 2018-11-13 Buy
Sigma-Aldrich P-044 Promethazine hydrochloride vial of 25 mg, certified reference material 044-25mg $52 2018-11-13 Buy
Sigma-Aldrich P-111 Promethazine hydrochloride 1.0 mg/mL (1% 1 M HCl in Methanol (as free base)), ampule of 1 mL, certified reference material 111-1ml $52 2018-11-13 Buy
Sigma-Aldrich P4651 Promethazine hydrochloride 25g $52.5 2018-11-13 Buy
Sigma-Aldrich PHR1467 Promethazine Hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material 1g $66.9 2018-11-20 Buy
TCI Chemical P2029 Promethazine Hydrochloride >98.0%(HPLC)(T) 25g $49 2018-11-22 Buy

Properties

Melting point: :230-232°C
Flash point: :9℃
storage temp.  :Refrigerator
solubility  :Very soluble in water, freely soluble in ethanol (96 per cent) and in methylene chloride.
form  :neat
PH :pH (50g/L, 25℃) : 4.0~6.0
λmax :297nm(H2O)(lit.)
Merck  :14,7786
BRN  :4166397
InChIKey :XXPDBLUZJRXNNZ-UHFFFAOYSA-N
CAS DataBase Reference :58-33-3(CAS DataBase Reference)
EPA Substance Registry System :10H-Phenothiazine- 10-ethanamine, N,N,.alpha.-trimethyl-, monohydrochloride(58-33-3)

Safety Information

Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P311 Call a POISON CENTER or doctor/physician.
P391 Collect spillage. Hazardous to the aquatic environment
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P333+P313 IF SKIN irritation or rash occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P501 Dispose of contents/container to..…

Description

Promethazine is a first generation histamine H1 receptor antagonist (Ki = 2.6 nM) whose antihistamine activity has been reported in guinea pigs and mice at ED50 values of 0.43 and 5.9 mg/kg, respectively. Promethazine can penetrate the CNS, depressing central H1 receptor activity, which may relate to its sedative properties, and can also inhibit muscarinic acetylcholine receptors (Ki = 22 nM). Furthermore, 32 mg/kg promethazine demonstrates antiemetic effects in ferret models of motion sickness or chemotherapy-induced nausea.

Related product price