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ChemicalBook >> CAS DataBase List >> p-Toluenesulfonyl Isocyanate

p-Toluenesulfonyl Isocyanate

p-Toluenesulfonyl Isocyanate price.
  • $7 - $650
  • Product name: p-Toluenesulfonyl Isocyanate
  • CAS: 4083-64-1
  • MF: C8H7NO3S
  • MW: 197.21
  • EINECS:223-810-8
  • MDL Number:MFCD00002030
  • Synonyms:4-Isocyanatosulphonyltoluene,;p-Toluenesulfonyl isocyanate, 96%, AcroSeal;Isocyanicacid, anhydride with p-toluenesulfonic acid (6CI);p-Toluenesulfonyl isocyanate 96%;p-Toluenesulfonyl isocyanate, 96%, SpcSeal;p-Toluenesulfonylisocyanate,95%;Benzenesulfonyl isocyanate, 4-methyl-;Benzenesulfonylisocyanate,4-methyl-
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  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • Frontier Specialty Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • SynQuest Laboratories
  • TCI Chemical
  • TRC
  • Usbiological
Package
  • 5g
  • 10x1ml
  • 10ml
  • 25g
  • 100g
  • 250g
  • 500g
  • ManufacturerAK Scientific
  • Product numberD380
  • Product descriptionp-Toluenesulfonyl isocyanate
  • Packaging5g
  • Price$21
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberD380
  • Product descriptionp-Toluenesulfonyl isocyanate
  • Packaging100g
  • Price$79
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA17492
  • Product descriptionp-Toluenesulfonyl isocyanate, 95%
  • Packaging25g
  • Price$20.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA17492
  • Product descriptionp-Toluenesulfonyl isocyanate, 95%
  • Packaging100g
  • Price$32.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberA17492
  • Product descriptionp-Toluenesulfonyl isocyanate, 95%
  • Packaging500g
  • Price$108.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA404059
  • Product descriptionp-Toluenesulfonyl isocyanate 99%
  • Packaging25g
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerFrontier Specialty Chemicals
  • Product numberJK303168
  • Product descriptionp-Toluenesulfonyl isocyanate 96%
  • Packaging25g
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerFrontier Specialty Chemicals
  • Product numberJK303168
  • Product descriptionp-Toluenesulfonyl isocyanate 96%
  • Packaging100g
  • Price$26
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number62180
  • Product descriptionp-Toluenesulfonyl isocyanate
  • Packaging25g
  • Price$650
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number41368
  • Product descriptionp-Toluenesulfonyl isocyanate for HPLC derivatization, ≥98.0% (GC)
  • Packaging10ml
  • Price$37.7
  • Updated2022-05-15
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number189278
  • Product descriptionp-Toluenesulfonyl isocyanate 97%
  • Packaging25g
  • Price$43.1
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number189278
  • Product descriptionp-Toluenesulfonyl isocyanate 97%
  • Packaging100g
  • Price$45.3
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number189278
  • Product descriptionp-Toluenesulfonyl isocyanate 96%
  • Packaging500g
  • Price$133
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number41368
  • Product descriptionp-Toluenesulfonyl isocyanate for HPLC derivatization, ≥98.0% (GC)
  • Packaging10x1ml
  • Price$192
  • Updated2022-05-15
  • Buy
  • ManufacturerSynQuest Laboratories
  • Product number8749-1-01
  • Product description4-Methylbenzene-1-sulfonyl isocyanate 98%
  • Packaging25g
  • Price$24
  • Updated2021-12-16
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  • ManufacturerTCI Chemical
  • Product numberT0998
  • Product descriptionp-Toluenesulfonyl Isocyanate >97.0%(T)
  • Packaging25g
  • Price$18
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific D380 p-Toluenesulfonyl isocyanate 5g $21 2021-12-16 Buy
AK Scientific D380 p-Toluenesulfonyl isocyanate 100g $79 2021-12-16 Buy
Alfa Aesar A17492 p-Toluenesulfonyl isocyanate, 95% 25g $20.65 2024-03-01 Buy
Alfa Aesar A17492 p-Toluenesulfonyl isocyanate, 95% 100g $32.65 2024-03-01 Buy
Alfa Aesar A17492 p-Toluenesulfonyl isocyanate, 95% 500g $108.65 2024-03-01 Buy
Ambeed A404059 p-Toluenesulfonyl isocyanate 99% 25g $7 2021-12-16 Buy
Frontier Specialty Chemicals JK303168 p-Toluenesulfonyl isocyanate 96% 25g $19 2021-12-16 Buy
Frontier Specialty Chemicals JK303168 p-Toluenesulfonyl isocyanate 96% 100g $26 2021-12-16 Buy
Medical Isotopes, Inc. 62180 p-Toluenesulfonyl isocyanate 25g $650 2021-12-16 Buy
Sigma-Aldrich 41368 p-Toluenesulfonyl isocyanate for HPLC derivatization, ≥98.0% (GC) 10ml $37.7 2022-05-15 Buy
Sigma-Aldrich 189278 p-Toluenesulfonyl isocyanate 97% 25g $43.1 2024-03-01 Buy
Sigma-Aldrich 189278 p-Toluenesulfonyl isocyanate 97% 100g $45.3 2024-03-01 Buy
Sigma-Aldrich 189278 p-Toluenesulfonyl isocyanate 96% 500g $133 2024-03-01 Buy
Sigma-Aldrich 41368 p-Toluenesulfonyl isocyanate for HPLC derivatization, ≥98.0% (GC) 10x1ml $192 2022-05-15 Buy
SynQuest Laboratories 8749-1-01 4-Methylbenzene-1-sulfonyl isocyanate 98% 25g $24 2021-12-16 Buy
TCI Chemical T0998 p-Toluenesulfonyl Isocyanate >97.0%(T) 25g $18 2024-03-01 Buy

Properties

Melting point :5°C
Boiling point :144 °C10 mm Hg(lit.)
Density :1.291 g/mL at 25 °C(lit.)
vapor pressure :1 mm Hg ( 100 °C)
refractive index :n20/D 1.534(lit.)
Flash point :>230 °F
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
form :Liquid
Specific Gravity :1.291.291
color :Clear colorless to yellow
Odor :acrid odor
Water Solubility :reacts
Sensitive :Moisture Sensitive
BRN :391287
InChIKey :VLJQDHDVZJXNQL-UHFFFAOYSA-N
LogP :0.6 at 30℃
CAS DataBase Reference :4083-64-1(CAS DataBase Reference)
NIST Chemistry Reference :4-Methylbenzenesulfonyl isocyanate(4083-64-1)
EPA Substance Registry System :Benzenesulfonyl isocyanate, 4-methyl- (4083-64-1)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled Sensitisation, respiratory Category 1 Danger GHS hazard pictograms P261, P285, P304+P341, P342+P311,P501
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

It is a reagent used to prepare acetylated syn-1,2-diols,oxazolidin-2-ones, 2,3-diamino acids, and N-tosylcarbonamides. -Toluenesulfonyl isocyanate has been used as derivatization reagent in determination of 3-α-hydroxy tibolone in human plasma by LC-MS/MS. It is also employed in the derivatization reagent in simultaneous quantitative analysis of diethylene glycol and propylene glycol in pharmaceutical products by HPLC and as reagent in the preparation of acetylated syn-1,2-diols, oxazolidin-2-ones, 2,3-diamino acids and N-tosylcarbonamides.

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