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ChemicalBook >> CAS DataBase List >> Trimetazidine dihydrochloride

Trimetazidine dihydrochloride

Trimetazidine dihydrochloride  price.
  • $29 - $1020
  • Product name: Trimetazidine dihydrochloride
  • CAS: 13171-25-0
  • MF: C14H24Cl2N2O3
  • MW: 339.26
  • EINECS:236-117-0
  • MDL Number:MFCD00243086
  • Synonyms:1-(2,3,4-TRIMETHOXYBENZYL)PIPERAZINE DIHYDROCHLORIDE;1-[(2,3,4-Trimethoxy-phenyl)methyl]piperazine Dihydrochloride;Vastarel F;Yoshimilon;1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride,Trimetazidine dihydrochloride;Trimetazidine 3HCl;Takkmint;Youmetazine
27 prices
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  • ACHEMBLOCK
  • AHH
  • AK Scientific
  • Cayman Chemical
  • Chemenu
  • Chem-Impex
  • Crysdot
  • DC Chemicals
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  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
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  • y0000093
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  • ManufacturerACHEMBLOCK
  • Product numberI-9663
  • Product description1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride 97%
  • Packaging1G
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberI-9663
  • Product description1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride 97%
  • Packaging5G
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1631
  • Product descriptionTrimetazidinedihydrochloride 98%
  • Packaging1g
  • Price$510
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10512
  • Product descriptionTrimetazidine2HCl
  • Packaging25mg
  • Price$29
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18165
  • Product descriptionTrimetazidine (hydrochloride) ≥98%
  • Packaging10mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18165
  • Product descriptionTrimetazidine (hydrochloride) ≥98%
  • Packaging25mg
  • Price$72
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number18165
  • Product descriptionTrimetazidine (hydrochloride) ≥98%
  • Packaging50mg
  • Price$116
  • Updated2024-03-01
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  • ManufacturerCayman Chemical
  • Product number18165
  • Product descriptionTrimetazidine (hydrochloride) ≥98%
  • Packaging100mg
  • Price$178
  • Updated2024-03-01
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  • ManufacturerChemenu
  • Product numberCM106475
  • Product description1-[(2,3,4-trimethoxyphenyl)methyl]piperazinedihydrochloride 98%
  • Packaging100g
  • Price$122
  • Updated2021-12-16
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  • ManufacturerChemenu
  • Product numberCM106475
  • Product description1-[(2,3,4-trimethoxyphenyl)methyl]piperazinedihydrochloride 98%
  • Packaging500g
  • Price$355
  • Updated2021-12-16
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  • ManufacturerChem-Impex
  • Product number38288
  • Product descriptionTrimetazidinedihydrochloride,98%(HPLC) 98%(HPLC)
  • Packaging5G
  • Price$57.12
  • Updated2021-12-16
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  • ManufacturerChem-Impex
  • Product number38288
  • Product descriptionTrimetazidinedihydrochloride,98%(HPLC) 98%(HPLC)
  • Packaging25G
  • Price$182.56
  • Updated2021-12-16
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  • ManufacturerCrysdot
  • Product numberCD31003899
  • Product descriptionTrimetazidinedihydrochloride 98+%
  • Packaging25g
  • Price$40
  • Updated2021-12-16
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  • ManufacturerCrysdot
  • Product numberCD31003899
  • Product descriptionTrimetazidinedihydrochloride 98+%
  • Packaging100g
  • Price$119
  • Updated2021-12-16
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  • ManufacturerCrysdot
  • Product numberCD31003899
  • Product descriptionTrimetazidinedihydrochloride 98+%
  • Packaging500g
  • Price$376
  • Updated2021-12-16
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  • ManufacturerDC Chemicals
  • Product numberDC9047
  • Product descriptionTrimetazidinedihydrochloride >98%
  • Packaging1g
  • Price$300
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
ACHEMBLOCK I-9663 1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride 97% 1G $50 2021-12-16 Buy
ACHEMBLOCK I-9663 1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride 97% 5G $100 2021-12-16 Buy
AHH API-1631 Trimetazidinedihydrochloride 98% 1g $510 2021-12-16 Buy
AK Scientific J10512 Trimetazidine2HCl 25mg $29 2021-12-16 Buy
Cayman Chemical 18165 Trimetazidine (hydrochloride) ≥98% 10mg $37 2024-03-01 Buy
Cayman Chemical 18165 Trimetazidine (hydrochloride) ≥98% 25mg $72 2024-03-01 Buy
Cayman Chemical 18165 Trimetazidine (hydrochloride) ≥98% 50mg $116 2024-03-01 Buy
Cayman Chemical 18165 Trimetazidine (hydrochloride) ≥98% 100mg $178 2024-03-01 Buy
Chemenu CM106475 1-[(2,3,4-trimethoxyphenyl)methyl]piperazinedihydrochloride 98% 100g $122 2021-12-16 Buy
Chemenu CM106475 1-[(2,3,4-trimethoxyphenyl)methyl]piperazinedihydrochloride 98% 500g $355 2021-12-16 Buy
Chem-Impex 38288 Trimetazidinedihydrochloride,98%(HPLC) 98%(HPLC) 5G $57.12 2021-12-16 Buy
Chem-Impex 38288 Trimetazidinedihydrochloride,98%(HPLC) 98%(HPLC) 25G $182.56 2021-12-16 Buy
Crysdot CD31003899 Trimetazidinedihydrochloride 98+% 25g $40 2021-12-16 Buy
Crysdot CD31003899 Trimetazidinedihydrochloride 98+% 100g $119 2021-12-16 Buy
Crysdot CD31003899 Trimetazidinedihydrochloride 98+% 500g $376 2021-12-16 Buy
DC Chemicals DC9047 Trimetazidinedihydrochloride >98% 1g $300 2021-12-16 Buy

Properties

Melting point :231-235 °C(lit.)
storage temp. :Refrigerator
solubility :Freely soluble in water, sparingly soluble in alcohol.
color :White to Off-White
Merck :14,9705
Stability :Hygroscopic
InChIKey :XIRALXKCBGTYSC-UHFFFAOYSA-N
CAS DataBase Reference :13171-25-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Trimetazidine dihydrochloride is the dihydrochloride salt of Trimetazidine. It is a drug used for the treatment of angina pectoris. It is capable of improving the left ventricular function in diabetic patients suffering coronary heart disease as well as treating the symptoms of patients suffering heart failure of different etiologies. It takes effects through acting as an anti- ischemic metabolic agent being capable of improving the utilization efficiency of myocardial glucose by inhibiting the metabolism of fatty acid (through inhibiting the activity of mitochondrial long- chain 3-ketoacyl coenzyme A Thiolase). The shift from fatty acid oxidation to glucose oxidation optimizes cellular energy process in cells exposed to hypoxia or ischaemia, further maintaining the intracellular ATP levels and ensuring the normal function of ionic pumps and transmembrane sodium-potassium flow to maintain cellular homeostasis.

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