404-82-0 Basic information More..
Product Name:Fenfluramine hydrochloride
Synonyms:FENFLURAMINE HYDROCHLORIDE MM(CRM STANDARD);N-Ethyl-a-methyl-3-(trifluoromethyl)benzeneethanamine Hydrochloride;(+)-n-ethyl-α-methyl-m-[trifluoromethyl]phenethylamine hydrochloride;BenzeneethanaMine,N-ethyl-a-Methyl-3-(trifluoroMethyl)-,hydrochloride (1:1);(+)-N-Ethyl-α-methyl-m-[trifluoromethyl]phenethylamine;n-ethyl-1-[3-(trifluoromethyl)phenyl]-propan-2-amine;N-ETHYL-ALPHA-METHYL-3-(TRIFLUOROMETHYL)PHENETHYLAMINE HYDROCHLORIDE;N-ETHYL-ALPHA-METHYL-M-(TRIFLUOROMETHYL)PHENETHYLAMINE HYDROCHLORIDE
CAS:404-82-0
MF:C12H17ClF3N
MW:267.72
EINECS:206-968-2
Mol File:404-82-0.mol
404-82-0

Use

Fenfluramine hydrochloride, (±)N-ethyl- -methyl-m-(trifluoromethyl)phenethylamine hydrochloride (Pondimin), isunique in this group of drugs, in that it tends to produce sedationrather than excitation. Effects are said to be mediatedprincipally by central serotoninergic, rather than central noradrenergic,mechanisms. In large doses in experimental animals,the drug is a serotonin neurotoxin.It was withdrawnfrom human use after reports of heart valve damage and pulmonaryhypertension. From its structure, more apolar or hydrophobiccharacter than amphetamine, tropism for serotoninergicneurons would be expected. Likewise, thestructure suggests an indirect mechanism. If an indirectmechanism were operative, then all postsynaptic 5-HT receptors could be activated. Evidence from several studies indicatesthat the 5-HT1B and the 5-HT2C receptors are mostresponsible for the satiety effects of 5-HT. 5-HT may alsoinfluence the type of food selected (e.g., lower-fat food intake).The(+) isomer, dexfenfluramine (Redux), has agreater tropism for 5-HT systems than the racemic mixture.It, too, was withdrawn because of toxicity.

Fenfluramine hydrochloride manufacturers

  • Fenfluramine hydrochloride
  • US $15.00-10.00 / KG
  • 2021-08-12
  • CAS:404-82-0
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
Information Error Report
Your Email:
404-82-0 Recommend Suppliers
Recommend You Select Member Companies...
Company Name: Shenzhen Nexconn Pharmatechs Ltd      Recommend     Complaint
Tel: +86-755-89396905
FAX:
Email: admin@nexconn.com
Nationality: China
Products Intro: Product Name:Fenfluramine hydrochloride
CAS:404-82-0
Purity:0.98 Package:1KG;10KG;50KG
CB Index: 58
WebSite: https://www.chemicalbook.com/ShowSupplierProductsList31188/0.htm
Related Information: Sales Network   Catalog(7836)   User Evaluation
Company Name: Hubei xin bonus chemical co. LTD      Recommend     Complaint
Tel: 86-13657291602
FAX: 027-59338440
Email: linda@hubeijusheng.com
Nationality: CHINA
Products Intro: Product Name:Fenfluramine hydrochloride
CAS:404-82-0
Purity:0.99 Package:5KG;1KG
CB Index: 58
WebSite: www.chemicalbook.com/ShowSupplierProductsList1549548/0.htm
Related Information: Sales Network   Catalog(22968)   User Evaluation
Company Name: CONIER CHEM AND PHARMA LIMITED      Recommend     Complaint
Tel:
FAX:
Email: sales@conier.com
Nationality: China
Products Intro: Product Name:fenfluramine hydrochloride
CAS:404-82-0
Purity:99% Package:1kg
CB Index: 58
WebSite: http://www.conier.com/
Related Information: Sales Network   Catalog(47465)   User Evaluation
Company Name: Career Henan Chemica Co      Recommend     Complaint
Tel: +86-0371-86658258
FAX: 0371-86658258
Email: laboratory@coreychem.com
Nationality: China
Products Intro: Product Name:fenfluramine hydrochloride
CAS:404-82-0
Purity:95%-99% crystal Liu Package:1KG;0.01USD
CB Index: 58
WebSite: https://www.coreychem.com/
Related Information: Sales Network   Catalog(30255)   User Evaluation
Company Name: Dideu Industries Group Limited      Recommend     Complaint
Tel: +86-29-89586680
FAX:
Email: 1026@dideu.com
Nationality: China
Products Intro: Product Name:Fenfluramine hydrochloride
CAS:404-82-0
Purity:0.999 Package:1g;1.1USD Remarks:FDA GMP CEP Approved Manufacturer
CB Index: 58
WebSite: www.dideu.com
Related Information: Sales Network   Catalog(29831)   User Evaluation
Company Name: Mainchem Co., Ltd.      Recommend    Complaint
Tel: +86-0592-6210733
FAX: +86-0592-6210733
Email: sale@mainchem.com
Products Intro: Product Name:Fenfluramine hydrochloride
CAS:404-82-0
   More...
CB Index: 55
WebSite: https://www.mainchem.com
Related Information: Sales Network   Catalog(32360)   User Evaluation(5)
Company Name: Chemsky (shanghai) International Co.,Ltd      Recommend    Complaint
Tel: 021-50135380
FAX:
Email: shchemsky@sina.com
Products Intro: Product Name:rac FenfluraMine Hydrochloride;N-Ethyl-α-Methyl-3-(trifluoroMethyl)benzeneethanaMine Hydrochloride; N-Ethyl-α-Methyl-M-(trifluoroMethyl)phenethylaMine Hydrochloride; Acino; AdipoMin; Obedrex; Pesos; Ponderal; PondiMin; Rotondin;
CAS:404-82-0
Purity:98+% Package:1Mg;5Mg;10Mg;50Mg;100Mg;500Mg   More...
CB Index: 60
WebSite: www.shchemsky.com
Related Information: Sales Network   Catalog(15421)   User Evaluation(2)
Company Name: Hangzhou Yuhao Chemical Technology Co., Ltd      Recommend    Complaint
Tel: 0571-82693216
FAX: +86-571-82880190
Email: info@yuhaochemical.com
Products Intro: Product Name:fenfluraMine hydrochloride
CAS:404-82-0
   More...
CB Index: 52
WebSite: www.chemyuhao.com
Related Information: Sales Network   Catalog(9394)   User Evaluation
1 2 3
Tag: 404-82-0