Momelotinib

1056634-68-4 Basic information More..

Product Name:	Momelotinib
Synonyms:	CYT387, >=98%;CYT 11387;CYT 387;N-(Cyanomethyl)-4-[2-[[4-(4-morpholinyl)phenyl]amino]-4-pyrimidinyl]benzamide;LM-1149;CYT 387(CYT 11387);N-(cyanoMethyl)-4-(2-(4-Morpholin-4-ylphenylaMino)pyriMidin-4-yl)benzaMide;MoMelotinib
CAS:	1056634-68-4
MF:	C23H22N6O2
MW:	414.46
EINECS:
Mol File:	1056634-68-4.mol

Use

Momelotinib (CYT387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM, ~10-fold selectivity versus JAK3. Phase 3.

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