PI3K / Akt / mTOR

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구조 화학 이름 CAS MF
Pictilisib Pictilisib 957054-30-7 C23H27N7O3S2
NVP-BEZ 235 NVP-BEZ 235 915019-65-7 C30H23N5O
BKM120 (NVP-BKM120, Buparlisib) BKM120 (NVP-BKM120, Buparlisib) 944396-07-0 C18H21F3N6O2
LY 294002 HYDROCHLORIDE LY 294002 HYDROCHLORIDE 154447-36-6 C19H17NO3
CAL-101 CAL-101 870281-82-6 C22H18FN7O
Temsirolimus Temsirolimus 162635-04-3 C56H87NO16
Perifosine (KRX-0401) Perifosine (KRX-0401) 157716-52-4 C25H52NO4P
MK-2206 2HCl MK-2206 2HCl 1032350-13-2 C25H21N5O
API-2 API-2 35943-35-2 C13H16N6O4
SB216763 SB216763 280744-09-4 C19H12Cl2N2O2
PP242 PP242 1092351-67-1 C16H16N6O
KU-0063794 KU-0063794 938440-64-3 C25H31N5O4
AZD-8055 AZD-8055 1009298-09-2 C25H31N5O4
GSK-2126458 GSK-2126458 1086062-66-9 C25H17F2N5O3S
XL147 XL147 956958-53-5 C21H16N6O2S2
5-(6-Quinoxalinylmethylene)-2,4-thiazolidinedione 5-(6-Quinoxalinylmethylene)-2,4-thiazolidinedione 648450-29-7 C12H7N3O2S
ZSTK474 ZSTK474 475110-96-4 C19H21F2N7O2
(S)-1-[4-[[2-(2-Aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-2-hydroxypropan-1-one (S)-1-[4-[[2-(2-Aminopyrimidin-5-yl)-7-methyl-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-6-yl]methyl]piperazin-1-yl]-2-hydroxypropan-1-one 1032754-93-0 C23H30N8O3S
3-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[5,6-e]pyrimidin-7-yl]-N-methylbenzamide 3-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[5,6-e]pyrimidin-7-yl]-N-methylbenzamide 1009298-59-2 C25H30N6O3
N-(2,3-Dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide N-(2,3-Dihydro-7,8-dimethoxyimidazo[1,2-c]quinazolin-5-yl)-3-pyridinecarboxamide 677338-12-4 C18H17N5O3
2-[(6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone 2-[(6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone 371242-69-2 C22H19N7O
LY2090314 LY2090314 603288-22-8 C28H25FN6O3
AZD5363 AZD5363 1143532-39-1 C21H25ClN6O2
ZOTAROLIMUS ZOTAROLIMUS 221877-54-9 C52H79N5O12
PIK-93 PIK-93 593960-11-3 C14H16ClN3O4S2
6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide 6-Amino-N-[3-[4-(4-morpholinyl)pyrido[3',2':4,5]furo[3,2-d]pyrimidin-2-yl]phenyl]-3-pyridinecarboxamide 371942-69-7 C25H21N7O3
OSU-03012 OSU-03012 742112-33-0 C26H19F3N4O
N-[4-[1-(1,4-Dioxaspiro[4.5]dec-8-yl)-4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-N'-methylurea N-[4-[1-(1,4-Dioxaspiro[4.5]dec-8-yl)-4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-N'-methylurea 1144068-46-1 C27H33N7O4
PF-4708671 PF-4708671 1255517-76-0 C19H21F3N6
AT7867 AT7867 857531-00-1 C20H20ClN3
N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea N-Ethyl-N'-[4-[5,6,7,8-tetrahydro-4-[(3S)-3-methyl-4-morpholinyl]-7-(3-oxetanyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea 1207360-89-1 C24H32N6O3
GSK-3BETA INHIBITOR XII GSK-3BETA INHIBITOR XII 601514-19-6 C18H14N4O2
2,6-PYRIDINEDIAMINE, N6-[2-[[4-(2,4-DICHLOROPHENYL)-5-(1H-IMIDAZOL-1-YL)-2-PYRIMIDINYL]AMINO]ETHYL]-3-NITRO- 2,6-PYRIDINEDIAMINE, N6-[2-[[4-(2,4-DICHLOROPHENYL)-5-(1H-IMIDAZOL-1-YL)-2-PYRIMIDINYL]AMINO]ETHYL]-3-NITRO- 252935-94-7 C20H17Cl2N9O2
PF-05212384 PF-05212384 1197160-78-3 C32H41N9O4
IPI 145 IPI 145 1201438-56-3 C22H17ClN6O
N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide N-[3-[[5-Iodo-4-[[3-[(2-thienylcarbonyl)amino]propyl]amino]-2-pyrimidinyl]amino]phenyl]-1-pyrrolidinecarboxamide 702675-74-9 C23H26IN7O2S
OSI-027 OSI-027 936890-98-1 C21H22N6O3
PaloMid 529 (P529) PaloMid 529 (P529) 914913-88-5 C24H22O6
A-674563 A-674563 552325-73-2 C22H22N4O
GSK2636771 GSK2636771 1372540-25-4 C22H22F3N3O3
GDC-0068 GDC-0068 1001264-89-6 C24H32ClN5O2
BIO BIO 667463-62-9 C16H10BrN3O2
PHT-427 PHT-427 1191951-57-1 C20H31N3O2S2
1-AZAKENPAULLONE 1-AZAKENPAULLONE 676596-65-9 C15H10BrN3O
42-(Dimethylphosphinate)rapamycin 42-(Dimethylphosphinate)rapamycin 572924-54-0 C53H84NO14P
AZD 1080 AZD 1080 612487-72-6 C19H18N4O2
SB 415286 SB 415286 264218-23-7 C16H10ClN3O5
4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE 4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE 327036-89-5 C10H10N2O2S
5-[[5-(4-Fluoro-2-hydroxyphenyl)-2-furanyl]methylene]-2,4-thiazolidinedione 5-[[5-(4-Fluoro-2-hydroxyphenyl)-2-furanyl]methylene]-2,4-thiazolidinedione 900515-16-4 C14H8FNO4S
PI-103 PI-103 371935-74-9 C19H16N4O3
4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)piperidin-4-aMine 4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)piperidin-4-aMine 885499-61-6 C18H20ClN5
BX-912 BX-912 702674-56-4 C20H23BrN8O
5-(4-aMino-1-isopropyl-1H-pyrazolo[3,4-d]pyriMidin-3-yl)benzo[d]oxazol-2-aMine 5-(4-aMino-1-isopropyl-1H-pyrazolo[3,4-d]pyriMidin-3-yl)benzo[d]oxazol-2-aMine 1224844-38-5 C15H15N7O
AR-A014418 AR-A014418 487021-52-3 C12H12N4O4S
CH5132799 CH5132799 1007207-67-1 C15H19N7O3S
AKT Kinase Inhibitor AKT Kinase Inhibitor 842148-40-7 C16H19N7O3
PI-3065 PI-3065 955977-50-1 C27H31FN6OS
BI-D1870 BI-D1870 501437-28-1 C19H23F2N5O2
PIK-294 PIK-294 900185-02-6 C28H23N7O2
WYE-687 WYE-687 1062161-90-3 C28H32N8O3
Bikinin Bikinin 188011-69-0 C9H9BrN2O3
PKI-402 PKI-402 1173204-81-3 C29H34N10O3
4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione 4-Benzyl-2-(naphthalen-1-yl)-[1,2,4]thiadiazolidine-3,5-dione 865854-05-3 C19H14N2O2S
AT-13148 AT-13148 1056901-62-2 C17H16ClN3O
GSK-2110183C GSK-2110183C 1047644-62-1 C18H17Cl2FN4OS
IM-12 IM-12 1129669-05-1 C22H20FN3O2
XL-388 XL-388 1251156-08-7 C23H22FN3O4S
AZD-2858 AZD-2858 486424-20-8 C21H23N7O3S
A66 A66 1166227-08-2 C17H23N5O2S2
VS-5584 VS-5584 1246560-33-7 C17H22N8O
9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one 9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one 1223001-51-1 C24H15F3N4O
Torin 1 Torin 1 1222998-36-8 C35H28F3N5O2
WAY-600 WAY-600 1062159-35-6 C28H30N8O
NVP-BGT226 NVP-BGT226 1245537-68-1 C28H25F3N6O2.C4H4O4
BAY 80-6946 (Copanlisib) BAY 80-6946 (Copanlisib) 1032568-63-0 C23H28N8O4
HS-173 HS-173 1276110-06-5 C21H18N4O4S
LY2584702 LY2584702 1082949-67-4 C21H19F4N7
LY-2584702 (tosylate salt) LY-2584702 (tosylate salt) 1082949-68-5 C28H27F4N7O3S
AS 604850 AS 604850 648449-76-7 C11H5F2NO4S
5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione 5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione 958852-01-2 C18H11N3O2S
GSK 2334470 GSK 2334470 1227911-45-6 C25H34N8O
2-[[(1R)-1-[7-methyl-2-(4-morpholinyl)-4-oxo-4h-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid 2-[[(1R)-1-[7-methyl-2-(4-morpholinyl)-4-oxo-4h-pyrido[1,2-a]pyrimidin-9-yl]ethyl]amino]benzoic acid 1173900-33-8 C22H24N4O4
CAY10505 CAY10505 1218777-13-9 C14H8FNO3S
BML-275 BML-275 1219168-18-9 C24H27Cl2N5O
CZC24832 CZC24832 1159824-67-5 C15H17FN6O2S
XL765 XL765 1349796-36-6 C31H29N5O6S
KP372-1 KP372-1 329710-24-9 C10H4N6O
3,3'-(2,4-Diamino-6,7-pteridinediyl)bisphenol 3,3'-(2,4-Diamino-6,7-pteridinediyl)bisphenol 677297-51-7 C18H14N6O2
PIK-293 PIK-293 900185-01-5 C22H19N7O
TG 100713 TG 100713 925705-73-3 C12H10N6O
7-benzyl-10-(2-Methylbenzyl)-2,6,7,8,9,10-hexahydroiMidazo[1,2-a]pyrido[4,3-d]pyriMidin-5(3H)-one 7-benzyl-10-(2-Methylbenzyl)-2,6,7,8,9,10-hexahydroiMidazo[1,2-a]pyrido[4,3-d]pyriMidin-5(3H)-one 41276-02-2 C24H26N4O
WYE-354 WYE-354 1062169-56-5 C24H29N7O5
PIK-75 Hydrochloride PIK-75 Hydrochloride 372196-77-5 C16H15BrClN5O4S
WZ4003 WZ4003 1214265-58-3 C25H29ClN6O3
5-(6-(3-Methoxyoxetan-3-yl)-4-Morpholinothieno[3,2-d]pyriMidin-2-yl)pyriMidin-2-aMine 5-(6-(3-Methoxyoxetan-3-yl)-4-Morpholinothieno[3,2-d]pyriMidin-2-yl)pyriMidin-2-aMine 1394076-92-6 C19H22N6O3S
MHY1485 MHY1485 326914-06-1 C17H21N7O4
H-89 DIHYDROCHLORIDE HYDRATE H-89 DIHYDROCHLORIDE HYDRATE 130964-39-5 C20H20BrN3O2S.2ClH.H2O
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