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| (1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL Basic information |
Product Name: | (1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL | Synonyms: | 1-((1S,2S);-1-Hydroxy-1-(4-hydroxyphenyl);propan-2-yl);(1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL;CP 101606;1-[(1S,2S)-2-Hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]-4-phenylpiperidin-4-ol;(1s,2s)-1-[4-[ hydroxylphenyl]- 2- ( 4-hydroxy-4-pheny1piperidino)-1- propanol;1-((1S,2S)-1-Hydroxy-1-(4-hydroxyphenyl)propan-2-yl)-4-phenylpiperidin-4-ol | CAS: | 134234-12-1 | MF: | C20H25NO3 | MW: | 327.42 | EINECS: | | Product Categories: | | Mol File: | 134234-12-1.mol | |
| (1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL Chemical Properties |
Boiling point | 534.4±50.0 °C(Predicted) | density | 1.228 | storage temp. | 2-8°C | solubility | DMSO: ≥35mg/mL | form | powder | pka | 9.99±0.26(Predicted) | color | white to tan | optical activity | [α]/D +50 to +60° (c=1, MeOH) |
Hazard Codes | T,N | Risk Statements | 25-36-50 | Safety Statements | 26-45-61 | RIDADR | 2811 | WGK Germany | 3 | HazardClass | IRRITANT | PackingGroup | Ⅲ |
| (1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL Usage And Synthesis |
Uses | Traxoprodil (CP101,606) is a potent and selective NMDA antagonist and protect hippocampal neurons with an IC50 of 10 nM. | Uses | CP-101,606 has been used as a N-methyl-D-aspartate (NMDA)?receptor antagonist to study its role in recovery of spinal cord injuries. | Brand name | Traxoprodil is INN. | General Description | CP-101,606 (Traxoprodil) is a substituted 4-phenylpiperidine and is localized in the fore brain neurons. | Biochem/physiol Actions | Traxoprodil (CP-101,606) is a potent noncompetitive antagonist of N-methyl-D-aspartate (NMDA) receptors, selective for the NR2B subunit. It has been shown to be neuroprotective in animal models of brain injury and stroke. |
| (1S,2S)-1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDINO)-1-PROPANOL Preparation Products And Raw materials |
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