2'-脱氧胞苷-5'-三磷酸三钠盐
| 中文名称 | 2'-脱氧胞苷-5'-三磷酸三钠盐 |
|---|---|
| 中文同义词 | 2'-脱氧胞苷-5'-三磷酸三钠盐(DCTP.NA3);100MM脱氧胞苷三磷酸溶液 (DCTP 100MM);胞嘧啶脱氧核糖 5ˊ-三磷酸三钠盐;脱氧胞苷 5ˊ-三磷酸三钠盐;三磷酸脱氧胞苷三钠盐;2'-脱氧胞嘧啶-5'-三磷酸三钠盐;2'-脱氧胞嘧啶-5'-三磷酸;2'-脱氧胞苷-5'-三磷酸三钠盐 |
| 英文名称 | Deoxycytidine triphosphate trisodium salt |
| 英文同义词 | 2'-DEOXYCYTIDINE 5'-TRIPHOSPHATE (SODIUM SALT);2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODIUM SALT;2'-DEOXYCYTIDINE-5'-TRIPHOSPHORIC ACID TRISODIUM SALT;Dctp-Na3;Deoxycytidine-5'-Triphosphoric Acid Trisodium Sal;dCTP,3Na;CYTIDINE 5''-(TETRAHYDROGEN TRIPHOSPHATE), 2''-DEOXY-, TRISODIUM SALT;((2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyltriphosphoric acid, trisodium salt |
| CAS号 | 109909-44-6 |
| 分子式 | C9H17N3NaO13P3 |
| 分子量 | 491.15 |
| EINECS号 | |
| 相关类别 | 植物激素及核酸类;生化试剂-植物激素及核酸类;通用生化试剂-核酸;PCR |
| Mol文件 | 109909-44-6.mol |
| 结构式 |  |
2'-脱氧胞苷-5'-三磷酸三钠盐 性质
| 储存条件 | -20°C |
|---|---|
| 溶解度 | 水：10mg/mL |
| 形态 | 结晶固体 |
| 水溶解性 | Water: 10 mg/ml |
| InChIKey | WBIPTAOOMJEGQO-JXXKLNQHNA-K |
| SMILES | N1(C=CC(N)=NC1=O)[C@H]1C[C@H](O)[C@@H](COP([O-])(=O)OP([O-])(=O)OP([O-])(=O)O)O1.[Na+].[Na+].[Na+] |&1:8,10,12,r| |
| CAS 数据库 | 109909-44-6(CAS DataBase Reference) |
Deoxycytidine triphosphate trisodium salt (dCTP trisodium salt) 是可用于 DNA 合成 (DNA synthesis) 的核苷三磷酸。Deoxycytidine triphosphate trisodium salt 可用于实时 PCR，cDNA 合成 和 DNA 测序等研究。
Assays of thirteen cell lines, derived from mouse lymphomas, myelomas, myeloid tumors, and a mastocytoma, for sensitivity to growth inhibition by 1-β-D-arabinofuranosylcytosine (ara-C) revealed a spectrum between the most and least sensitive which differed 100-fold from each other. An inverse correlation between sensitivity and cellular Deoxycytidine triphosphate (2′-Deoxycytidine-5′-triphosphate, dCTP) content is found, and this suggested that sensitivity of cells might be increased if the dCTP content was lowered during cell exposure to ara-C.
Deoxycytidine triphosphate trisodium salt is a phosphoethanolamine cytidylyltransferase substrate.