BENZP-DINITRIDE-THIO-KETONE

BENZP-DINITRIDE-THIO-KETONE Basic information
Product Name:BENZP-DINITRIDE-THIO-KETONE
Synonyms:BENZP-DINITRIDE-THIO-KETONE;7-Chloro-5-phenyl-1H-benzo[e][1,4]diazepine-2(3H)-thione;Thionordiazepam;7-Chloro-5-phenyl-1H-benzo[e][1,4]diazepine-2(3H);7-chloro-5-phenyl-1,3-dihydro-1,4-benzodiazepine-2-thione;Benzodiazepines Intermediate 1;2H-1,4-Benzodiazepine-2-thione, 7-chloro-1,3-dihydro-5-phenyl-;BENZP-DINIRIDE-THIO-KETONE
CAS:4547-02-8
MF:C15H11ClN2S
MW:286.78
EINECS:
Product Categories:Aromatics;Heterocycles;Sulfur & Selenium Compounds
Mol File:4547-02-8.mol
BENZP-DINITRIDE-THIO-KETONE Structure
BENZP-DINITRIDE-THIO-KETONE Chemical Properties
Melting point 256-258?C (dec.)
Boiling point 408.9±55.0 °C(Predicted)
density 1.32±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility DMF: 15 mg/ml; DMF:PBS (pH 7.2) (1:1): 0.5 mg/ml; DMSO: 10 mg/ml; Ethanol: 1 mg/ml
form A crystalline solid
pka9.72±0.40(Predicted)
Safety Information
MSDS Information
BENZP-DINITRIDE-THIO-KETONE Usage And Synthesis
Chemical PropertiesYellow Solid
Uses7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione (cas# 4547-02-8) is a positive allosteric modulator for the muscarinic M1 receptor, which could be a potential treament for the Alzheimer's disease or Schizophrenia.
BENZP-DINITRIDE-THIO-KETONE Preparation Products And Raw materials
Preparation Products2-(2-ACETYLHYDRAZINO)-7-CHLORO-5-PHENYL-3H-1,4-BENZODIAZEPINE
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