兰色染料
中文名称 | 兰色染料 |
---|---|
中文同义词 | 汽巴蓝 3GA 琼脂糖;汽巴蓝F3GA;C.I.活性蓝2;兰色染料;活性蓝2;汽巴蓝/兰色染料;蓝色染料;化合物 T19049 |
英文名称 | REACTIVE BLUE 2 |
英文同义词 | REACTIVE BLUE 2 C.I. NO. 61211;Procion Blue HB, pure;2-Anthracenesulfonic acid, 1-amino-4-4-4-chloro-6-3(or 4)-sulfophenylamino-1,3,5-triazin-2-ylamino-3-sulfophenylamino-9,10-dihydro-9,10-dioxo-;C.I.REACTIVEBLUE2;CIBRACONBLUEF3GA;Reactive blue 2 (C.I. 61211);Kayacion Blue A-B;1-Amino-4-[[4-[[4-chloro-6-[[4-(sodiooxysulfonyl)phenyl]amino]-1,3,5-triazin-2-yl]amino]-3-(sodiooxysulfonyl)phenyl]amino]-9,10-dihydro-9,10-dioxo-2-anthracenesulfonic acid sodium salt |
CAS号 | 12236-82-7 |
分子式 | C29H20ClN7O11S3 |
分子量 | 774.16 |
EINECS号 | 235-465-0 |
相关类别 | Affinity Chromatography;Dye Resins;Protein Chromatography;C;Stains and Dyes;Stains&Dyes, A to |
Mol文件 | 12236-82-7.mol |
结构式 |
兰色染料 性质
储存条件 | 2-8°C |
---|---|
溶解度 | 可溶于水中 |
形态 | 生理盐水悬浮液 |
颜色 | 深蓝 |
稳定性 | 稳定的。与强氧化剂不相容。 |
CAS 数据库 | 12236-82-7 |
EPA化学物质信息 | 2-Anthracenesulfonic acid, 1-amino-4-[[4-[[4-chloro-6-[[3(or 4)-sulfophenyl]amino]-1,3,5-triazin-2-yl]amino]-3-sulfophenyl]amino]-9,10-dihydro-9,10-dioxo- (12236-82-7) |
Reactive Blue 2 is used as an ATP receptor antagonist and induces Ca 2+ oscillations in HeLa cells. Reactive Blue 2 enhances a Ca 2+ response to histamine that is linked to the PLC cascade. Reactive Blue 2 may activate the PLC cascade in an extracellular Ca 2+ -dependent manner and induce Ca 2+ oscillations. The application of Reactive Blue 2 increases K + secretion in a dose-dependent manner, and this increase is characterized as a peak followed by a partial relaxation to a steady-state. Reactive Blue 2 has antagonistic activities at P2Y4, and the antagonist potency at P2Y4 paralleled the potency of K+ secretion.The anthraquinone dye reactive blue 2 is found to be a potent inhibitor of a protein kinase isolated and purified from thylakoids. The mode of inhibition is noncompetitive, with a K i of 8 μM for the membrane-bound kinase, and 6 microM for the purified kinase. The inhibitor does not modify the substrate preference of the endogenous kinase and could be removed from the membrane by washing. Reactive blue 2 selectively inhibits responses mediated via the P2ypurinoceptor, at least within a limited concentration range. In preparations where the tone has been raised with noradrenaline, ATP and 2-methylthio ATP, but not α,β-methylene ATP, produce relaxations of the vessel. These relaxations are inhibited in the presence of reactive blue 2. Reactive blue 2, at concentrations of 0.3-10 μM blocks the ATP-induced oscillation in a concentration-dependent manner.
提供商 | 语言 |
---|---|
英文
|
|
英文
|
更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
---|---|---|---|---|---|
2024/08/19 | HY-D0965 | Procion Blue HB | 5 mg | 312元 | |
2024/08/19 | HY-D0965 | 兰色染料 Procion Blue HB | 12236-82-7 | 10mg | 500元 |