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BENFLUOREX HYDROCHLORIDE

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CAS:23602-78-0
Purity:97% Package:1KG;2USD
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CAS:23602-78-0
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CAS:23602-78-0
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Products Intro: Product Name:benzoic acid 2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino]ethyl ester; hydron; chloride
CAS:23602-78-0
Purity:0.97 Package:mgs,gs,kgs Remarks:A816795

BENFLUOREX HYDROCHLORIDE manufacturers

  • BENFLUOREX HYDROCHLORIDE
  • $2.00 / KG
  • 2020-01-08
  • CAS:23602-78-0
  • Min. Order: 1KG
  • Purity: 97%
  • Supply Ability: 100g , 1kg, 5kg , 50kg
BENFLUOREX HYDROCHLORIDE Basic information
Product Name:BENFLUOREX HYDROCHLORIDE
Synonyms:benzoic acid 2-[1-[3-(trifluoromethyl)phenyl]propan-2-ylamino]ethyl ester;Ethanol, 2-[[1-methyl-2-[3-(trifluoromethyl)phenyl]ethyl]amino]-, benzoate;jp992;Minolip;n-(2-hydroxyethyl)-alpha-methyl-m-trifluoromethyl-phenethylaminbenzoate;N-(2-Hydroxyethyl)-alpha-methyl-m-trifluoromethylphenethylamine benzoate;n-(2-hydroxyethyl)-alpha-methyl-m-trifluoromethylphenethylaminebenzoate;Phenethylamine, N-(2-hydroxyethyl)-alpha-methyl-m-trifluoromethyl-, benzoate
CAS:23602-78-0
MF:C19H20F3NO2
MW:351.36
EINECS:245-777-9
Product Categories:NULL;MINOLIP
Mol File:23602-78-0.mol
BENFLUOREX HYDROCHLORIDE Structure
BENFLUOREX HYDROCHLORIDE Chemical Properties
Boiling point 420.5±45.0 °C(Predicted)
density 1.183±0.06 g/cm3(Predicted)
pka8.23±0.10(Predicted)
Safety Information
WGK Germany 2
RTECS KL8275000
ToxicityLD50 oral in mouse: 2300mg/kg
MSDS Information
BENFLUOREX HYDROCHLORIDE Usage And Synthesis
OriginatorMediator,Servier,France,1976
Usesantihyperlipoproteinemic
Manufacturing ProcessTo a solution of 24.7 parts of 1-(m-trifluoromethylphenyl)-2-(β- hydroxyethyl)amino propane in 140 parts of anhydrous benzene, there were added successively 15 parts of 4.7N hydrochloric ether and a solution of 14 parts of benzoyl chloride in 24 parts of anhydrous benzene. The addition required 10 minutes, the reaction mixture was then refluxed for 8 hours.
The solid product was collected by filtration and after recrystallization from 230 parts of ethyl acetate, there were obtained 15 parts of 1-(mtrifluoromethylphenyl)- 2-(β-benzoyloxyethyl)amino propane hydrochloride melting at 161°C.
10 parts hydrochloride are put in suspension in 100 parts of water, 80 parts ether are added, then 10 parts of a concentrated solution of ammonium hydroxide. The mixture is stirred a few minutes until the salt is dissolved, then the ethered solution is poured off and dried. After the ether is eliminated, 9 parts of 1-(m-trifluoromethylphenyl)-2-(β- benzoyloxyethyl)amino propane are obtained; the base is a colorless oil.
Therapeutic FunctionAntihyperlipidemic, Cardiovascular
BENFLUOREX HYDROCHLORIDE Preparation Products And Raw materials
Raw materialsBenzoyl chloride
Tag:BENFLUOREX HYDROCHLORIDE(23602-78-0) Related Product Information
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