| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:ANTI-NEUROFILAMENT 200
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-Neurofilament 200 antibody produced in rabbit
Purity:IgG fraction of antiserum, buffered aqueous solution Package:.2ML Remarks:N4142-.2ML
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| Company Name: |
Riedel-de Haen AG
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| Tel: |
800 558-9160 |
| Email: |
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| Products Intro: |
Purity:clone NE14, ascites fluid Remarks:clone 2E8, purified immunoglobulin, buffered aqueous solution
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| Company Name: |
SIGMA-RBI
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| Tel: |
800 736 3690 (Orders) |
| Email: |
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| Products Intro: |
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| | ANTI-NEUROFILAMENT 200 Basic information |
| Product Name: | ANTI-NEUROFILAMENT 200 | | Synonyms: | ANTI-NF-H;ANTI-NEUROFILAMENT 200;ANTI-NEUROFILAMENT, BOVINE, 200KD;ANTI-NEUROFILAMENT HEAVY;ANTI-NEUROFILAMENT HEAVY CHAIN (HUMAN) CLONE NF-01;ANTI-NEUROFILAMENT NF-H;ANTI-NEUROFILAMENT P (200 KD);ANTI-NEUROFILAMENT, RAT, 200 KD | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-NEUROFILAMENT 200 Structure]() |
| | ANTI-NEUROFILAMENT 200 Chemical Properties |
| storage temp. | −20°C | | form | buffered aqueous solution |
| | ANTI-NEUROFILAMENT 200 Usage And Synthesis |
| Uses | Monoclonal Anti-Neurofilament 200 antibody produced in mouse has been used in
- immunohistochemistry
- immunolabeling
- immunofluorescence
| | Uses | Anti-neurofilament 200 antibody produced in rabbit has been used for immunolabeling.
Anti-neurofilament 200 antibody produced in rabbit has been used:
- for detection of neurofilaments using immunohistological staining
- in human astrocytoma cell line
- in post-mortem brain sections
- in human cremaster muscles
- for detection of neurofilaments by immunofluorescence staining in lumbar spinal cord sections of mice
| | General Description | Neurofilament 200, also known as neurofilament heavy polypeptide (NEFH), is encoded by the gene mapped to human chromosome 22q12.2. The encoded protein has a molecular mass of 200kDa and belongs to the group of type IV intermediate filaments which are key constituents of the neuronal cytoskeleton. NEFH contains C-terminal motifs involved in the formation of sidearm projections which cross-link the neurofilaments. | | Biochem/physiol Actions | Neurofilament 200 plays a vital role in cytoarchitecture organization. Downregulated expression of the gene has been observed in schizophrenia patients. Loss of gene expression is associated with the development of prostate carcinoma. Mutation in the gene leads to sporadic amyotrophic lateral sclerosis (ALS). Neurofilament 200 assembly during development is critical for normal functioning of neuronal cells. Mutations in gene encoding neurofilaments is associated with neurological disorder called the Charcot–Marie–Tooth. |
| | ANTI-NEUROFILAMENT 200 Preparation Products And Raw materials |
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