- alpha-Cyano-4-hydroxycinnamic acid
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- $12.50 / 25KG
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2020-06-02
- CAS:28166-41-8
- Min. Order: 1KG
- Purity: 99.50% in stock CAS 28166-41-8
- Supply Ability: 55 MT per month CAS 28166-41-8
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| | ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Basic information |
| | ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Chemical Properties |
| Melting point | 245-250 °C(lit.) | | Boiling point | 324.41°C (rough estimate) | | density | 1.3175 (rough estimate) | | refractive index | 1.5400 (estimate) | | storage temp. | 2-8°C | | solubility | methanol: 10 mg/mL, clear | | form | powder | | pka | 0.85±0.10(Predicted) | | color | yellow | | BRN | 3271427 | | InChIKey | AFVLVVWMAFSXCK-VMPITWQZSA-N | | CAS DataBase Reference | 28166-41-8(CAS DataBase Reference) |
| | ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Usage And Synthesis |
| Chemical Properties | yellow crystalline powder | | Uses | α-Cyano-4-hydroxycinnamic acid(CHC) was used as a matrix for peptides and nucleotides in mass spectroscopic analysis. It was used in encapsulation of CHC into NaY zeolite. It was used as matrix to investigate the activity of the paclitaxel derivatives using several well-established in vitro angiogenesis assays. | | Uses | inhibitor of mitochondrial pyruvate transport | | Uses | α-Cyano-4-hydroxycinnamic acid (CHC) was used in encapsulation of CHC into NaY zeolite. It was used as matrix to investigate the activity of the paclitaxel derivatives using several well-established in vitro angiogenesis assays. | | Definition | ChEBI: Alpha-cyano-4-hydroxycinnamic acid is a monohydroxycinnamic acid that is 4-hydroxycinnamic acid in which the hydrogen alpha- to the carboxy group is replaced by a cyano group. It is used as a matrix in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of peptides and oligonucleotides. It has a role as a MALDI matrix material. It is a nitrile, a member of phenols and a monohydroxycinnamic acid. | | General Description | α-Cyano-4-hydroxycinnamic acid is the commonly used matrix for analyzing peptides by matrix-assisted laser desorption/ionization mass spectrometry. It inhibits the monophenolase activity and diphenolase activity of mushroom tyrosinase. | | Biochem/physiol Actions | α-Cyano-4-hydroxycinnamic acid acts as a specific inhibitor of monocarboxylic acid transport, including lactate and pyruvate transport. It is also reported to block β-cell apical anion exchange (IC50 of 2.4 mM). | | storage | Store at +4°C |
| | ALPHA-CYANO-4-HYDROXYCINNAMIC ACID Preparation Products And Raw materials |
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