| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Anti-infective agent 3
CAS:2521629-86-5
Package:25mg/RMB 10600;100mg/RMB 17500;50mg/RMB 13800
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1,4-Naphthalenedione, 2-(2-chloro-5-pyrimidinyl)- manufacturers
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| | 1,4-Naphthalenedione, 2-(2-chloro-5-pyrimidinyl)- Basic information |
| | 1,4-Naphthalenedione, 2-(2-chloro-5-pyrimidinyl)- Chemical Properties |
| Boiling point | 519.1±50.0 °C(Predicted) | | density | 1.478±0.06 g/cm3(Predicted) | | pka | -1.98±0.22(Predicted) |
| | 1,4-Naphthalenedione, 2-(2-chloro-5-pyrimidinyl)- Usage And Synthesis |
| Uses | Anti-infective agent 3 (compound 3l) shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC50 values of 0.47 and 0.13 μM, respectively. Anti-infective agent 3 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 4 μg/mL[1]. | | References | [1] Kalt MM, et al. Palladium-catalysed synthesis of arylnaphthoquinones as antiprotozoal and antimycobacterial agents. Eur J Med Chem. 2020 Dec 1;207:112837. DOI:10.1016/j.ejmech.2020.112837 |
| | 1,4-Naphthalenedione, 2-(2-chloro-5-pyrimidinyl)- Preparation Products And Raw materials |
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