- Senkyunolide A
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- $0.00 / 25kg
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2024-04-12
- CAS:63038-10-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 2000ton
- Senkyunolide H
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- $0.00 / 25kg
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2024-04-12
- CAS:63038-10-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 2000ton
- Senkyunolide A
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- $0.00 / 20mg
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2023-02-24
- CAS:63038-10-8
- Min. Order: 5mg
- Purity: ≥98%(HPLC)
- Supply Ability: 10 g
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| (3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one Basic information |
Product Name: | (3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one | Synonyms: | (3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one;(S)-3-Butyl-4,5-dihydroisobenzofuran-1(3H)-one;1(3H)-Isobenzofuranone, 3-butyl-4,5-dihydro-, (S)-;(-)-Sedanenolide;(3S)-3-Butyl-4,5-dihydro-1(3H)-isobenzofuranone;(S)-Sedanenolide;3-Butyl-4,5-dihydrophthalide;1(3H)-Isobenzofuranone, 3-butyl-4,5-dihydro-, (3S)- | CAS: | 63038-10-8 | MF: | C12H16O2 | MW: | 192.26 | EINECS: | | Product Categories: | | Mol File: | 63038-10-8.mol | |
| (3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one Chemical Properties |
storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C | solubility | DMF: 5 mg/ml; DMSO: 5 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml | LogP | 1.775 (est) |
| (3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one Usage And Synthesis |
Description | Senkyunolide A is a phthalide originally isolated from celery seed essential oil that has cytoprotective and antiproliferative activities. It protects against cell injury induced by corticosterone in PC12 cells in a time-dependent manner when used at concentrations ranging from 0.125 to 0.5 mg/ml and reduces corticosterone-induced apoptosis at a concentration of 0.5 mg/ml. It also reverses increases in protein levels of phosphatase 2A (PP2A) and α-synuclein and reverses decreases in the phosphorylated forms of PP2A and α-synuclein. Senkyunolide A inhibits cell proliferation of HT-29 colon cancer (IC50 = 54.17 μM) but not non-cancerous human CCD-18Co colon cells (IC50 = 109.11 μM). | Definition | ChEBI: Senkyunolide is a member of 2-benzofurans. |
| (3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one Preparation Products And Raw materials |
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