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Sodium Phosphate, Dibasic

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Sodium Phosphate, Dibasic Basic information
Product Name:Sodium Phosphate, Dibasic
Synonyms:Sodium phosphate dibasic Vetec(TM) reagent grade, 99%;di-Sodium hydrogen phosphate anhydrous for analysis EMSURE ACS,Reag. Ph Eur;Sodium phosphate dibasic anhydrous, free-flowing, Redi-Dri, ACS reagent, >=99%;SODIUM PHOSPHATE DIBASIC BIOXTRA;SODIUM PHOSPHATE DIBASIC SOLUTION 0.;SODIUM PHOSPHATE DIBASIC, BIOREAGENT;SODIUM PHOSPHATE DIBASIC, REAGENTPLU;SODIUM PHOSPHATE, DIBASIC MOLECULAR*
CAS:7558-79-4
MF:Na2HPO4
MW:141.96
EINECS:231-448-7
Product Categories:metal phosphate compound;Chemistry;Inorganics;Food Additives;7558-79-4
Mol File:7558-79-4.mol
Sodium Phosphate, Dibasic Structure
Sodium Phosphate, Dibasic Chemical Properties
Melting point 243-245 °C
density 1.064 g/mL at 20 °C
bulk density880kg/m3
vapor density 4.9 (vs air)
vapor pressure 0Pa at 20℃
FEMA 2398 | DISODIUM PHOSPHATE
storage temp. Store at +5°C to +30°C.
solubility H2O: 0.5 M at 20 °C, clear, colorless
form powder
color White
PH8.9-9.2 (25℃, 50g/L in water)
pka(1) 2.15, (2) 6.82, (3) 12.38 (at 25℃)
Odorodorless
biological sourcesynthetic
Water Solubility >=10 g/100 mL at 20 ºC
Sensitive Hygroscopic
λmaxλ: 260 nm Amax: 0.019
λ: 280 nm Amax: 0.016
Merck 14,8659
Stability:Stable. Incompatible with strong acids. Hygroscopic.
Major ApplicationPFAS testing
Cosmetics Ingredients FunctionsFRAGRANCE
ANTICORROSIVE
BUFFERING
Cosmetic Ingredient Review (CIR)Sodium Phosphate, Dibasic (7558-79-4)
InChI1S/2Na.H3O4P/c;;1-5(2,3)4/h;;(H3,1,2,3,4)/q2*+1;/p-2
InChIKeyBNIILDVGGAEEIG-UHFFFAOYSA-L
SMILES[Na+].[Na+].[H]OP([O-])([O-])=O
LogP-2.15
CAS DataBase Reference7558-79-4(CAS DataBase Reference)
EPA Substance Registry SystemDisodium phosphate (7558-79-4)
Absorption≤0.01 at 260nm
≤0.01 at 280nm
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25
RIDADR UN 3077 9 / PGIII
WGK Germany 3
RTECS WC4500000
3
TSCA TSCA listed
HazardClass 9
HS Code 28352200
Storage Class11 - Combustible Solids
Hazardous Substances Data7558-79-4(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: > 2000 mg/kg
MSDS Information
ProviderLanguage
Disodium hydrogenorthophosphate English
SigmaAldrich English
ACROS English
ALFA English
Sodium Phosphate, Dibasic Usage And Synthesis
DescriptionSodium phosphate dibasic is highly hygroscopic and water soluble. Useful in conjunction with Sodium Phosphate, Monobasic in the preparation of biological buffers. It is commonly used in biological assay buffers. Sodium is required for nerve and muscle functioning. Sodium Phosphate Dibasic can be used as a dietary supplement and as a nutrient. Sodium hydrogen phosphate is used in food and water treatment in conjunction with trisodium phosphate.In foods, it is used to adjust pH. In water treatment, It retards calcium scale formation. It is also found in some detergents and cleaning agents. This product is known to be Used in many applications including the purification of antibodies. It is used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy.
Chemical PropertiesSodium hydrogen phosphate,NaH2P04·H20, is hygroscopic, transparent, water-soluble crystals. Used as a purgative, reagent,and buffer.
Chemical PropertiesThe anhydrous compound is white crystalline powder; hygroscopic; density 1.70 g/cm3; converts to sodium pyrophosphate at 240°C; soluble in water; 874 SODIUM PHOSPHATE, DIBASIC insoluble in alcohol. The dihydrate is a crystalline powder or granular solid; density 2.066 g/cm3 at 15°C; loses water of crystallization at 92.5°C. The heptahydrate is a powdered or granular crystalline solid; density 1.679 g/cm3; loses five molecules of water at 48°C. The dodecahydrate is made up of translucent crystals or granules; density 1.524 g/cm3; readily loses five water molecules on exposure to air at ambient temperature; melts at 35°C when the salt contains all water of crystallization; loses all water at 100°C. All the hydrates are soluble in water and insoluble in alcohol.
Chemical PropertiesDisodium phosphate is anhydrous or contains two molecules of water of hydration
Physical propertiesThe anhydrous compound is white crystalline powder; hygroscopic; density 1.70 g/cm3; converts to sodium pyrophosphate at 240°C; soluble in water;insoluble in alcohol.
The dihydrate is a crystalline powder or granular solid; density 2.066 g/cm3 at 15°C; loses water of crystallization at 92.5°C.
The heptahydrate is a powdered or granular crystalline solid; density 1.679 g/cm3; loses five molecules of water at 48°C.
The dodecahydrate is made up of translucent crystals or granules; density 1.524 g/cm3; readily loses five water molecules on exposure to air at ambient temperature; melts at 35°C when the salt contains all water of crystallization; loses all water at 100°C.
All the hydrates are soluble in water and insoluble in alcohol.
OccurrenceDisodium phosphate is anhydrous or contains two molecules of water of hydration
UsesSodium Phosphate Dibasic is used as an in conjunction with trisodium phosphate in foods and water treatment. In foods, it is used to adjust pH. In water treatment, It retards calcium scale formation. It is also found in some detergents and cleaning agents. Sodium Phosphate Dibasic is used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy.
UsesIt is used in pH buffer solutions.
UsesSodium Phosphate, Dibasic is used as a laboratory reagent and a buffer in chemical analysis. Other uses are in manufacturing ceramics, detergents, and enamels; as a mordant in dyeing; for fireproofing paper and wood; for weighting and printing silk; in the treatment of boiler water; as a sequestrant in food; as a dietary supplement; in soldering enamels; and in fertilizers. It is used therapeutically as a cathartic.
PreparationDibasic sodium phosphate is prepared by treating phosphoric acid with a slight excess of sodium carbonate. The solution is boiled to expel carbon dioxide. Upon cooling dodecahydrate crystallizes out. Heating dodecahydrate at 100°C forms the anhydrous salt.
H3PO4 + Na2CO3 → Na2HPO4 + CO2 + H2O
Dibasic sodium phosphate also is prepared by reacting dibasic calcium phosphate with sodium carbonate. The product calcium carbonate precipitates leaving dibasic sodium salt in the solution. The solution on cooling yields crystals of hydrated product.
CaHPO4 + Na2CO3 → CaCO3 + Na2HPO4
DefinitionChEBI: Disodium hydrogenphosphate is a sodium phosphate.
General DescriptionSodium phosphate dibasic in combination with sodium phosphate monobasic is used in the preparation of oral sodium phosphate solution (OSPS), which is a purgative used for bowel cleansing before colonoscopy.
Flammability and ExplosibilityNon flammable
Biochem/physiol ActionsSodium phosphate dibasic is an important component of running buffer of denaturing gel electrophoresis. It induces glomerular calcification as well as other nephrotic syndrome in Sprague-Dawley rats.
Safety ProfilePoison by intravenous route. Moderately toxic by intraperitoneal, subcutaneous, and intramuscular routes. Mildly toxic by ingestion. A skin and eye irritant. When heated to decomposition it emits toxic fumes of POx and Na2O. See also PHOSPHATES.
Purification MethodsCrystallise the salt twice from warm water, by cooling. Dry in air, then in an oven overnight at 130o. It should be dried before use as it is slightly hygroscopic. It forms di-, hepta-and deca-hydrates.
Toxics Screening LevelThe initial threshold screening level (ITSL) for disodium hydrogen phosphate is 10 μg/m3 (annual averaging time) based on the Environmental Protection Agency’s (EPA’s) reference concentration (RfC) value for phosphoric acid (EPA, 1995). The ITSL value was established by AQD on August 1, 2012 (MDEQ, 2012; see attached).
Tag:Sodium Phosphate, Dibasic(7558-79-4) Related Product Information
FERRIC PHOSPHATE Sodium Phosphate Monobasic Monohydrate Hydrogen Trisodium phosphate Calcium phosphate Ethylenediaminetetraacetic acid disodium salt Ammonium dihydrogen phosphate Zinc phosphate Potassium Phosphate Monobasic Creatine phosphate Sodium phosphate monobasic Sodium Monofluorophosphate Ammonium phosphate dibasic Potassium Phosphate Dibasic Potassium phosphate tribasic CERIUM(III) CHLORIDE Calcium silicate Calcium chloride Dibasic Sodium Phosphate Sodium Hydrogenphosphate Sodium Phosphate Dibasic Anhydrous

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