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| | (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Basic information |
| Product Name: | (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate | | Synonyms: | Intedanib Impurity D;Nintedanib Impurity 34;Nintedanib-011;Nintedanib impurity 10/(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate;(Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)meth...;1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-(methylamino)phenyl]amino]phenylmethylene]-2-oxo-, methyl ester, (3Z)-;Nintedanib Impurity q;(3Z)?-2,?3-Dihydro-?3-?[[[4-?(methylamino)?phenyl]?amino]?phenylmethylene]?-?2-?oxo-?1H-?Indole-?6-?carboxylic Acid Methyl Ester | | CAS: | 1987887-92-2 | | MF: | C24H21N3O3 | | MW: | 399.44 | | EINECS: | | | Product Categories: | | | Mol File: | 1987887-92-2.mol |  |
| | (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Chemical Properties |
| Melting point | 273 - 276°C | | Boiling point | 641.3±55.0 °C(Predicted) | | density | 1.316±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator, under inert atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 11.16±0.20(Predicted) | | form | Solid | | color | Yellow to Orange |
| | (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Usage And Synthesis |
| Uses | (3Z)?-2,?3-Dihydro-?3-?[[[4-?(methylamino)?phenyl]?amino]?phenylmethylene]?-?2-?oxo-?1H-?Indole-?6-?carboxylic Acid Methyl Ester is an impurity of Nintedanib (N478290), an angiokinase inhibitor and is used in the treatment of idiopathic pulmonary fibrosis. Also inhibits the process blood vessel formation which may be used to assist in cancer therapy. |
| | (Z)-methyl 3-(((4-(methylamino)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylate Preparation Products And Raw materials |
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