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4'-HYDROXYCHALCONE

4'-HYDROXYCHALCONE Suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Email: ivan@atkchemical.com
Products Intro: CAS:2657-25-2
Purity:0.99 Package:5G,10G,25G,50G,100G,250G,1KG
Company Name: Shanghai Zheyan Biotech Co., Ltd.
Tel: 18017610038
Email: zheyansh@163.com
Products Intro: Product Name:2-Benzal-4-Hydroxyacetophenone
CAS:2657-25-2
Purity:HPLC>=98% Package:100mg
Company Name: career henan chemical co
Tel: +86-0371-86658258
Email: sales@coreychem.com
Products Intro: Product Name:4'-HYDROXYCHALCONE
CAS:2657-25-2
Purity:95% Package:1KG;1USD
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 18871490254
Email: linda@hubeijusheng.com
Products Intro: Product Name:4-HYDROXYCHALCONE
CAS:2657-25-2
Purity:0.99 Package:5KG;1KG
Company Name: Chongqing Chemdad Co., Ltd
Tel: +86-023-61398051 +8613650506873
Email: sales@chemdad.com
Products Intro: Product Name:4'-HYDROXYCHALCONE
CAS:2657-25-2
Purity:0.98 Package:1kg,2kg,5kg,10kg,25kg

4'-HYDROXYCHALCONE manufacturers

  • 4'-HYDROXYCHALCONE
  • 4'-HYDROXYCHALCONE pictures
  • $0.00 / 1kg
  • 2022-09-28
  • CAS:2657-25-2
  • Min. Order: 1kg
  • Purity: 98%
  • Supply Ability: 1Ton
  • 4'-HYDROXYCHALCONE
  • 4'-HYDROXYCHALCONE  pictures
  • $1.00 / 1KG
  • 2019-07-06
  • CAS:2657-25-2
  • Min. Order: 1KG
  • Purity: 95%
  • Supply Ability: 500KG
4'-HYDROXYCHALCONE Basic information
Product Name:4'-HYDROXYCHALCONE
Synonyms:2-Benzal-4'-hydroxyacetophenone 2-Benzylidene-4'-hydroxyacetophenone;1-(4-Hydroxyphenyl)-3-phenyl-2-propen-1-one;1-(p-Hydroxyphenyl)-3-phenyl-2-propene-1-one;4'-Hydroxychalcone,97%;4'-Hydroxychalcone 98%;HYDROXYCHALCONE, 4-(RG);4'-Hydroxychalcone98%;HYDROXYCHALCONE, 4'-
CAS:2657-25-2
MF:C15H12O2
MW:224.25
EINECS:
Product Categories:Chalcones;Biochemistry;Flavonoids
Mol File:2657-25-2.mol
4'-HYDROXYCHALCONE Structure
4'-HYDROXYCHALCONE Chemical Properties
Melting point 174-178 °C
Boiling point 419.6±45.0 °C(Predicted)
density 1.191±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2) (1:4): 0.2 mg/ml
form powder to crystal
pka7.72±0.15(Predicted)
color Light orange to Yellow to Green
BRN 2049150
InChIKeyUAHGNXFYLAJDIN-IZZDOVSWSA-N
LogP3.650 (est)
CAS DataBase Reference2657-25-2(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 37/39-26-37
HS Code 29145090
MSDS Information
ProviderLanguage
ACROS English
ALFA English
4'-HYDROXYCHALCONE Usage And Synthesis
Description4''-hydroxy Chalcone is a chalcone metabolite with diverse biological activities. It is formed when chalcone is metabolized by the cytochrome (CYP) P450 isoform CYP1A1 or CYP2C6. 4''-hydroxy Chalcone is estrogenic in MCF-7 cells and is cytotoxic at concentrations higher than 100 nM. It inhibits TNF-α-induced NF-κB signaling and the trypsin-, chymotrypsin-, and caspase-like proteolytic activities of the 26S proteasome in K562 cells in a dose-dependent manner. 4''-hydroxy Chalcone reduces growth of K562, U937, and Jurkat cancer cell lines in a dose-dependent manner without effecting viability of peripheral blood mononuclear cells (PBMCs). It also inhibits glutathione reductase (GSH-RD; IC50 = 47.3 μM) in vitro in a reversible and non-competitive manner.
Chemical Propertiesyellow-cream powder
Uses4''-Hydroxychalcone is a chalone derivative that exhibits moderate to good antiviral activity against tobacco mosaic virus (TMV).
Usesantineoplastic,
DefinitionChEBI: A member of the class of chalcones that is trans-chalcone substituted by a hydroxy group at position 4'.
4'-HYDROXYCHALCONE Preparation Products And Raw materials
Tag:4'-HYDROXYCHALCONE(2657-25-2) Related Product Information
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