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Oleyl alcohol

Oleyl alcohol Suppliers list
Company Name: Mainchem Co., Ltd.
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Products Intro: Product Name:Oleyl alcohol
CAS:143-28-2
Company Name: Hubei Jusheng Technology Co.,Ltd.
Tel: 86-155-27864001
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Products Intro: Product Name:Oleyl alcohol
CAS:143-28-2
Purity:99% Package:5KG;1KG Remarks:C18H36O
Company Name: J & K SCIENTIFIC LTD.  
Tel: 400-666-7788 +86-10-82848833
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Products Intro: Product Name:Oleyl Alcohol
CAS:143-28-2
Purity:60.0%(GC) Package:25ML,500ML
Company Name: Meryer (Shanghai) Chemical Technology Co., Ltd.  
Tel: +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
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Products Intro: Product Name:Oleyl Alcohol
CAS:143-28-2
Purity:>60.0%(GC) Package:25ML;500ML Remarks:O0058
Company Name: 3B Pharmachem (Wuhan) International Co.,Ltd.  
Tel: 86-21-50328103 * 801、802、803、804 Mobile:18930552037
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Products Intro: Product Name:Oleyl alcohol
CAS:143-28-2
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
Oleyl alcohol Basic information
Product Name:Oleyl alcohol
Synonyms:unjecol50;unjecol70;unjecol90;DELTA 9 OLEYL ALCOHOL;CIS-9-OCTADECEN-1-OL;CIS-9-OCTADECENE-1-OL;(9Z)-9-Octadecen-1-ol;(z)-9-octadecen-1-o
CAS:143-28-2
MF:C18H36O
MW:268.48
EINECS:205-597-3
Product Categories:Acyclic;Alkenes;Biochemicals and Reagents;Building Blocks;Chemical Synthesis;Fatty Acids and conjugates;Fatty Acyls;Fatty Alcohols;Lipids;Monoenoic fatty acids;Organic Building Blocks;Unsaturated Fatty Acids and Derivatives;Biochemistry;Higher Fatty Acids & Higher Alcohols;Unsaturated Higher Alcohols
Mol File:143-28-2.mol
Oleyl alcohol Structure
Oleyl alcohol Chemical Properties
Melting point 0-5.0 °C(lit.)
Boiling point 207 °C13 mm Hg(lit.)
density 0.849 g/mL at 25 °C(lit.)
vapor pressure 10.64 hPa (195 °C)
refractive index n20/D 1.46(lit.)
FEMA 4363 | CIS-9-OCTADECENOL
Fp >230 °F
storage temp. −20°C
solubility Soluble in ethanol (95%), and ether; practically insoluble in water.
form Viscous Liquid
color Clear almost colorless to yellow
Water Solubility Miscible with alcohol and ether. Slightly miscible with carbon tetrachloride. Immiscible with water.
Merck 14,6831
BRN 1723962
Stability:Stable. Combustible. Incompatible with strong acids, strong oxidizing agents.
CAS DataBase Reference143-28-2(CAS DataBase Reference)
NIST Chemistry ReferenceOleyl Alcohol(143-28-2)
EPA Substance Registry System9-Octadecen-1-ol, (9Z)-(143-28-2)
Safety Information
Hazard Codes Xi
Risk Statements 38
Safety Statements 26-36
WGK Germany -
RTECS RG4120000
TSCA Yes
HS Code 29052990
Hazardous Substances Data143-28-2(Hazardous Substances Data)
ToxicityLD50 orally in Rabbit: > 5000 mg/kg
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
ALFA English
Oleyl alcohol Usage And Synthesis
Chemical PropertiesColourless or light yellow liquid.
Chemical PropertiesOleyl alcohol occurs as a pale yellow oily liquid that gives off acrid fumes when heated.
Usesoleyl alcohol is an emollient, solvent, viscosity-increasing agent, and carrier employed in a wide variety of cosmetic formulations including makeup, skin care, and hand and body preparations. oleyl alcohol is an unsaturated fatty alcohol found in fish oils and can also be produced synthetically. According to some sources, it is comedogenic and has a mild irritancy potential.
DefinitionChEBI: A long chain fatty alcohol that is octadecanol containing a double bond located at position 9 (the Z-geoisomer).
UsesChiefly in the manufacture of its sulfuric esters which are detergents and wetting agents, as an antifoam agent; metal cutting lubricant; in carbon paper, stencil paper, printing ink; as a plasticizer; for softening and lubricating textile fabrics; carrier for medicaments.
Production MethodsOleyl alcohol occurs naturally in fish oils. Synthetically, it can be prepared from butyl oleate by a Bouveault–Blanc reduction with sodium and butyl alcohol. An alternative method of manufacture is by the hydrogenation of triolein in the presence of zinc chromite.
Brand nameWitcohol 85 (Witco); Witcohol 90 (Witco).
Pharmaceutical ApplicationsOleyl alcohol is mainly used in topical pharmaceutical formulations and has been used in transdermal delivery formulations.It has been utilized in the development of biodegradable injectable thermoplastic oligomers,and in aerosol formulations of insulin and albuterol.
Therapeutically, it has been suggested that oleyl alcohol may exhibit antitumor properties via transmembrane permeation.
SafetyOleyl alcohol is mainly used in topical pharmaceutical formulations and is generally regarded as a nontoxic and nonirritant material at the levels employed as an excipient. However, contact dermatitis due to oleyl alcohol has been reported.
The results of acute oral toxicity and percutaneous studies in animals with products containing 8% oleyl alcohol indicate a very low toxicity. Formulations containing 8% or 20% oleyl alcohol administered by gastric intubation, at doses up to 10 g/kg bodyweight, caused no deaths and no toxic effects in rats.
storageThe bulk material should be stored in a well-closed container in a cool, dry, place.
Purification MethodsPurify it by fractional crystallisation at -40o from acetone, then distil it under vacuum. [Beilstein 2 IV 2204.]
Regulatory StatusIncluded in the FDA Inactive Ingredients Database (topical emulsions and ointments). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
Oleyl alcohol Preparation Products And Raw materials
Raw materialsSodium-->Acetic anhydride-->ETHYL OLEATE
Preparation ProductsMethyl hexanoate-->polyoxyalkylene phosphate-->emulsifier VO series
Tag:Oleyl alcohol(143-28-2) Related Product Information
Cholesteryl oleate Ursolic acid OLEIC ANHYDRIDE UVAOL alpha-Amyrin Enoxolone ALPHA-HEDERIN ECHINOCYSTIC ACID EC 4.1.1.31 (+)-Cloprostenol Oleyl alcohol ENOLASE Ethyl acetate 1-Dodecanol DEOXYNIVALENOL Pregnenolone (-)-alpha-Terpineol Terpineol