| Company Name: |
S.Z. PhyStandard Bio-Tech. Co., Ltd.
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| Tel: |
0755-4000505016 13380397412 |
| Email: |
3001272453@qq.com |
| Products Intro: |
Product Name:Nintedanib Impurity 8
CAS:2093243-16-2
Purity:98% HPLC Package:10mg;50mg;100mg
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| Company Name: |
Beijing Comparison Pharmaceutical Technology Co., Ltd
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| Tel: |
010-52878169 15701683040 |
| Email: |
sales@bjcomparison.com |
| Products Intro: |
Product Name:methyl(Z)-3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate
CAS:2093243-16-2
Purity:>=98% Package:100mg
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| Company Name: |
ChemStrong Scientific Co.,Ltd
|
| Tel: |
0755-66853366 13670046396 |
| Email: |
sales@chem-strong.com |
| Products Intro: |
Product Name:Nintedanib Impurity 3
CAS:2093243-16-2
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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| | (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Basic information |
| Product Name: | (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate | | Synonyms: | (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;Nintedanib impurity 12/Methyl (Z)-3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate;Nintedanib-013-Z;Nidanibu Impurity 8;Nintedanib impurities11;1H-Indole-6-carboxylic acid, 2,3-dihydro-3-(hydroxyphenylmethylene)-2-oxo-, methyl ester, (3Z)- | | CAS: | 2093243-16-2 | | MF: | C17H13NO4 | | MW: | 295.29 | | EINECS: | | | Product Categories: | | | Mol File: | 2093243-16-2.mol |  |
| | (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Chemical Properties |
| Melting point | >215°C (dec.) | | Boiling point | 536.9±50.0 °C(Predicted) | | density | 1.357±0.06 g/cm3(Predicted) | | storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly, Heated) | | form | Solid | | pka | 4.50±1.00(Predicted) | | color | Yellow to Dark Yellow |
| | (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Usage And Synthesis |
| Uses | (Z)-Methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate is a useful intermediate for the preparation of nintedanib esylate. Nintedanib is a drug for the treatment of idiopathic pulmonary fibrosis. |
| | (Z)-methyl 3-(hydroxy(phenyl)methylene)-2-oxoindoline-6-carboxylate Preparation Products And Raw materials |
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