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| | (S)-4-Hydroxy-2-pyrrolidinone Basic information |
| | (S)-4-Hydroxy-2-pyrrolidinone Chemical Properties |
| Melting point | 156-159 °C (lit.) | | alpha | -41 º (c=% in ethanol) | | Boiling point | 363.6±35.0 °C(Predicted) | | density | 1.292±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | Slightly soluble[in water] | | Water Solubility | Slightly soluble in water | | pka | 13.62±0.20(Predicted) | | form | Solid | | color | White to off-white | | optical activity | [α]23/D 43°, c = 1 in ethanol | | BRN | 1524192 | | InChIKey | IOGISYQVOGVIEU-VKHMYHEASA-N | | CAS DataBase Reference | 68108-18-9(CAS DataBase Reference) |
| | (S)-4-Hydroxy-2-pyrrolidinone Usage And Synthesis |
| Chemical Properties | White crystal | | Uses | The (S)-enantiomer intermediate in the preparation of Oxiracetam | | Uses | (S)-(?)-4-Hydroxy-2-pyrrolidinone can be used as a starting material in the preparation of:
- Biologically significant pyrrolo[1,2:1′,2′]azepino[5,6-b]indole derivatives.
- Substituted azepanes by reacting with various aldehydes via photochemical [5+2] cycloaddition.
| | General Description | 4-Hydroxy-2-pyrrolidinone is an important building block found in many bioactive compounds like streptopyrrolidine. It can be used as an intermediate in the synthesis of various γ-amino acids (GABA) and substituted 2-pyrrolidinones like cynometrine and cynodine. |
| | (S)-4-Hydroxy-2-pyrrolidinone Preparation Products And Raw materials |
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