Choline dihydrogencitrate salt

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Products Intro: Product Name:Choline dihydrogencitrate salt
CAS:77-91-8
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CAS:77-91-8
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CAS:77-91-8
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CAS:77-91-8
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Products Intro: Product Name:Choline dihydrogencitrate salt
CAS:77-91-8
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Choline dihydrogencitrate salt Basic information
Product Name:Choline dihydrogencitrate salt
Synonyms:Cholinvel;Citracol;Colicitrin;Coline citrate;Coline dihydrogen citrate;Delichol;2-(carboxymethyl)-2,4-dihydroxy-4-keto-butyrate;2-(carboxymethyl)-2,4-dihydroxy-4-oxobutanoate
CAS:77-91-8
MF:C6H7O7.C5H14NO
MW:295.29
EINECS:201-068-6
Product Categories:Biochemistry;Vitamin Related Compounds;Vitamins
Mol File:77-91-8.mol
Choline dihydrogencitrate salt Structure
Choline dihydrogencitrate salt Chemical Properties
Melting point 105-107.5°
storage temp. 2-8°C
solubility DMSO (Slightly, Heated), Methanol (Slightly), Water (Slightly)
form Solid
color White to Off-White
Water Solubility almost transparency
Merck 14,2207
Stability:Hygroscopic
LogP-1.721 (est)
CAS DataBase Reference77-91-8(CAS DataBase Reference)
EPA Substance Registry SystemCholine citrate (1:1) (77-91-8)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
WGK Germany 2
RTECS GA2582000
HS Code 29231000
MSDS Information
ProviderLanguage
SigmaAldrich English
Choline dihydrogencitrate salt Usage And Synthesis
Chemical PropertiesWhite crystalline powder
OriginatorChothyn, Flint, US,1945
UsesCholine Dihydrogen Citrate can be used to synthesize compounds that can improve the photosynthetic efficiency of plants. It can also be used for synthesizing cleaning compounds that can be used for dishwashing, oven cleaning, microwave oven cleaning, floor cleaning, or surface cleaning. Furthermore, Choline Dihydrogen Citrate can potentially be used in the treatment of multiple sclerosis. Additionally, Choline Dihydrogen Citrate can also be use as a component of a nutritional supplement that can be used for improving cerebral activity.
Manufacturing Process30 lb of trimethylamine were added to 70.4 lb of methyl alcohol to which 9.2 lb of water had previously been added. To the resulting solution in a closed vessel 23 lb of ethylene oxide gas were introduced and the resulting mixture then maintained at a temperature of 16 C to 30 C and agitated for 6 hours. During the reaction the pressure in the reaction vessel varied from about 17.5 psi at the start of the reaction to 0 psi at the end of the reaction. The resulting solution was then added with agitation to a refluxing solution of 40 liters of isopropyl alcohol containing 95 lb of citric acid dissolved therein. This mixture was then cooled to 0°C and held at that temperature overnight. The white crystalline choline dihydrogen citrate which formed was separated from the solvent mixture by filtration and dried in vacuo. 117 lb of anhydrous, crystalline choline dihydrogen citrate having a purity of 99.6% were obtained. This was a yield of 78% based on the amount of trimethylamine employed.
Therapeutic FunctionLipotropic
Biochem/physiol ActionsAcyl group acceptor
Choline dihydrogencitrate salt Preparation Products And Raw materials
Raw materialsCitric acid-->Trimethylamine-->ETHYLENE OXIDE
Tag:Choline dihydrogencitrate salt(77-91-8) Related Product Information
Choline hydroxide Tetraethylammonium hydroxide Ammonium ferric citrate Calcium citrate Ammonium citrate dibasic Tetraethylammonium bromide Disodium citrate SODIUM DIHYDROGEN CITRATE Mosapride citrate Hydroxyethyl starch Zinc citrate Citicoline sodium Sildenafil citrate Citric acid Sodium citrate POTASSIUM DIHYDROGEN CITRATE Hydroxyethyl Cellulose Citiolone